N21200
2-硝基-1,4-苯二胺
95%
别名:
1,4-二氨基-2-硝基苯, 2-硝基对苯二胺
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关于此项目
线性分子式:
O2NC6H3(NH2)2
化学文摘社编号:
分子量:
153.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
226-164-5
Beilstein/REAXYS Number:
2210195
MDL number:
产品名称
2-硝基-1,4-苯二胺, 95%
InChI
1S/C6H7N3O2/c7-4-1-2-5(8)6(3-4)9(10)11/h1-3H,7-8H2
InChI key
HVHNMNGARPCGGD-UHFFFAOYSA-N
SMILES string
Nc1ccc(N)c(c1)[N+]([O-])=O
assay
95%
form
powder
mp
135-138 °C (lit.)
Quality Level
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signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
>372.2 °F - Pensky-Martens closed cup
flash_point_c
> 189 °C - Pensky-Martens closed cup
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
M Nakao et al.
Chemical & pharmaceutical bulletin, 39(1), 177-180 (1991-01-01)
Reductive metabolism of the hair dye constituent, nitro-p-phenylenediamine (2-nitro-1,4-diaminobenzene, NPDA), and its acetylated metabolite, NPDA N4-acetate, was investigated with rat liver subcellular fractions, microsomes and cytosol. Under anaerobic conditions, these compounds were reduced to their corresponding amines by these fractions.
M Nakao et al.
Journal of toxicology and environmental health, 11(1), 93-100 (1983-01-01)
The distribution, excretion, and metabolism of nitro-p-phenylenediamine, a constituent of hair dye, was studied after administration of [14C]nitro-p-phenylene-diamine (2.6 mg/30 microCi/kg) to male rats. After intraperitoneal administration, 37.4% of the radioactivity administered was excreted in the urine and 54.3% in
I S Grover et al.
Mutation research, 300(1), 1-3 (1993-06-01)
The water and chloroform extracts of guava were tested for their antimutagenicity. The water extract was effective in inactivating the mutagenicity of direct-acting mutagens, e.g., 4-nitro-o-phenylenediamine, sodium azide, and the S9-dependent mutagen, 2-aminofluorene, in the tester strains of Salmonella typhimurium.
J J Yourick et al.
Toxicology and applied pharmacology, 166(1), 13-23 (2000-06-30)
2-Nitro-p-phenylenediamine (2NPPD) is a dye used in semipermanent and permanent (tinting color) hair dye formulations. National Toxicology Program toxicology and carcinogenesis testing of 2NPPD has raised concerns about its safety. Therefore, we initiated in vitro studies to measure absorption and
S Grégoire et al.
Skin pharmacology and physiology, 21(2), 89-97 (2008-01-12)
Percutaneous penetration studies are usually performed in human skin samples set up in a Franz cell device. The ability to perform these studies may depend on the availability of skin samples. Reconstructed skin models are an interesting alternative to overcome
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