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Merck
CN

N14204

Sigma-Aldrich

4-(4-硝基苄基)吡啶

98%

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About This Item

经验公式(希尔记法):
C12H10N2O2
CAS号:
分子量:
214.22
Beilstein:
170877
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

方案

98%

表单

crystals

mp

69-71 °C (lit.)

SMILES字符串

[O-][N+](=O)c1ccc(Cc2ccncc2)cc1

InChI

1S/C12H10N2O2/c15-14(16)12-3-1-10(2-4-12)9-11-5-7-13-8-6-11/h1-8H,9H2

InChI key

MNHKUCBXXMFQDM-UHFFFAOYSA-N

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应用

用于烷基化试剂的测试 以及用于光谱法测定光气。

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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S K Dangwal
Industrial health, 32(1), 41-47 (1994-01-01)
A reagent consisting of 0.4% of nitrobenzyl pyridine and 0.5% of sodium acetate in ethanol was found to be applicable as a sampling and coloring solution to a sensitive and relatively specific spectrophotometric determination of phosgene. This method is a
Use of 4-(nitrobenzyl)pyridine (4-NBP) to test mutagenic potential of slow-reacting epoxides, their corresponding olefins, and other alkylating agents.
J H Kim et al.
Bulletin of environmental contamination and toxicology, 49(6), 879-885 (1992-12-01)
Marcio Fronza et al.
Phytochemistry, 78, 107-119 (2012-03-23)
Abietane diterpenes, especially those containing quinone moieties, are often reported to have cytotoxic effects on cancer cell lines. They deserve greater attention because several cancer chemotherapeutic agents also possess the quinone structural feature. To date, very little is known about
Rafael Gómez-Bombarelli et al.
Chemical research in toxicology, 25(6), 1176-1191 (2012-04-07)
Alkylating agents are considered to be archetypal carcinogens. One suitable technique to evaluate the activity of alkylating compounds is the NBP assay. This method is based on the formation of a chromophore in the reaction between the alkylating agent and
Marina González-Pérez et al.
Chemical research in toxicology, 25(12), 2755-2762 (2012-11-23)
The chemical reactivity of the mutagenic epoxides (EP) propylene oxide (PO), 1,2-epoxybutane (1,2-EB), and cis- and trans-2,3-epoxybutane (cis- and trans-2,3-EB) with 4-(p-nitrobenzyl)pyridine (NBP), a bionucleophile model for S(N)2 alkylating agents with high affinity for the guanine-N7 position, was investigated kinetically.

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