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质量水平
方案
97%
表单
crystals
mp
118-121 °C (lit.)
SMILES字符串
CNC(N)=S
InChI
1S/C2H6N2S/c1-4-2(3)5/h1H3,(H3,3,4,5)
InChI key
KQJQICVXLJTWQD-UHFFFAOYSA-N
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Danger
危险声明
危险分类
Acute Tox. 2 Oral - Aquatic Chronic 2
储存分类代码
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
T S Plantinga et al.
Clinical pharmacology and therapeutics, 102(6), 1017-1024 (2017-05-10)
Agranulocytosis is a rare and serious adverse effect of antithyroid drugs, with unknown etiology. The present study aimed to uncover genetic susceptibility and underlying mechanisms of antithyroid drug-induced agranulocytosis (ATDAC). We studied two independent families with familial Graves' disease, of
Shruti Sharma et al.
International journal of molecular sciences, 14(1), 255-272 (2013-01-25)
Congenital heart defects with increased pulmonary blood flow (PBF) result in pulmonary endothelial dysfunction that is dependent, at least in part, on decreases in nitric oxide (NO) signaling. Utilizing a lamb model with left-to-right shunting of blood and increased PBF
T Mizutani et al.
Chemical research in toxicology, 13(3), 170-176 (2000-03-22)
In mice depleted of GSH by treatment with buthionine sulfoximine (BSO), methimazole (2-mercapto-1-methylimidazole, MMI) causes liver injury characterized by centrilobular necrosis of hepatocytes and an increase in serum alanine transaminase (SALT) activity. MMI requires metabolic activation by both P450 monooxygenase
S P Gorman et al.
The Journal of applied bacteriology, 60(4), 319-325 (1986-04-01)
The cidal activity of the antimicrobial agent, noxythiolin, was investigated against a laboratory strain and a fresh isolate of Candida albicans. The order of resistance to noxythiolin was hyphal form (isolate) greater than or equal to 25 degrees C-grown blastospores
M Yabuki et al.
European journal of drug metabolism and pharmacokinetics, 22(1), 25-33 (1997-01-01)
Metabolism of 4-[1-(2-fluoro-4-biphenylyl)ethyl]-2-methylaminothiazole (SM-8849), a novel immunomodulatory agent, in rats was investigated. By co-chromatography with authentic samples, desmethylated (SM-8800) p-hydroxylated (SL-5512) and desmethylated-p-hydroxylated SM-8849 (SL-5515) were detected in the bile. Thermospray mass spectrometry (TSP-MS) analysis of five metabolites isolated from
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