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Merck
CN

M6250

Sigma-Aldrich

2-巯基乙醇

≥99.0%

别名:

β-巯基乙醇, 2-羟乙基硫醇, BME, 硫代二甘醇

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About This Item

线性分子式:
HSCH2CH2OH
CAS号:
分子量:
78.13
Beilstein:
773648
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
方案:
≥99.0%
沸点:
157 °C (lit.)
蒸汽压:
1 mmHg ( 20 °C)

蒸汽密度

2.69 (vs air)

质量水平

蒸汽压

1 mmHg ( 20 °C)

方案

≥99.0%

表单

liquid

expl. lim.

18 %

浓度

14.3 M (pure liquid)

折射率

n20/D 1.500 (lit.)

pH值(酸碱度)

4.5-6 (20 °C, 500 g/L)

沸点

157 °C (lit.)

密度

1.114 g/mL at 25 °C (lit.)

储存温度

2-8°C

SMILES字符串

OCCS

InChI

1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2

InChI key

DGVVWUTYPXICAM-UHFFFAOYSA-N

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一般描述

2-巯基乙醇是一种硫醇化合物,常用作有机反应中的还原剂。

应用

2-巯基乙醇广泛用于延迟溶液中的生物化合物氧化。
BME 适用于在聚丙烯酰胺凝胶电泳前还原蛋白质二硫键,通常用于 SDS-PAGE 的样品缓冲液,浓度为 5%。 切割分子间(亚基之间)二硫键允许蛋白质的亚基在 SDS-PAGE 上独立分离。 切割分子内(亚基内)二硫键可使亚基完全变性,从而使每个肽根据其链长迁移,而不受二级结构的影响。

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警示用语:

Danger

危险分类

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1A - STOT RE 2 Oral

靶器官

Liver,Heart

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

165.2 °F - closed cup

闪点(°C)

74 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

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分析证书(COA)

Lot/Batch Number

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Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines.
Asfari M, et al.
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Silver stain for proteins in polyacrylamide gels: a modified procedure with enhanced uniform sensitivity.
Morrissey JH.
Analytical Biochemistry, 117(2), 307-310 (1981)
Katharina Rothe et al.
Blood, 123(23), 3622-3634 (2014-04-24)
Previous studies demonstrated that imatinib mesylate (IM) induces autophagy in chronic myeloid leukemia (CML) and that this process is critical to cell survival upon therapy. However, it is not known if the autophagic process differs at basal levels between CML
Manching Ku et al.
PLoS genetics, 4(10), e1000242-e1000242 (2008-11-01)
In embryonic stem (ES) cells, bivalent chromatin domains with overlapping repressive (H3 lysine 27 tri-methylation) and activating (H3 lysine 4 tri-methylation) histone modifications mark the promoters of more than 2,000 genes. To gain insight into the structure and function of
E M Michalak et al.
Cell death and differentiation, 15(6), 1019-1029 (2008-02-09)
The ability of p53 to induce apoptosis in cells with damaged DNA is thought to contribute greatly to its tumour suppressor function. P53 has been proposed to induce apoptosis via numerous transcriptional targets or even by direct cytoplasmic action. Two

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