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Merck
CN

L091000

Sigma-Aldrich

N,N-二甲基甲酰胺

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别名:
DMF, NSC 5356
线性分子式:
HCON(CH3)2
CAS号:
分子量:
73.09
Beilstein:
605365
EC 号:
MDL编号:
UNSPSC代码:
12352111
PubChem化学物质编号:
NACRES:
NA.51

蒸汽密度

2.5 (vs air)

质量水平

蒸汽压

2.7 mmHg ( 20 °C)

类型

for DNA synthesis

产品线

Proligo Reagents

形式

liquid

自燃温度

833 °F

expl. lim.

15.2 %

储存条件

dry at room temperature

杂质

≤200 ppm water content (Karl Fischer)
≤9 ppm Amine content

颜色

clear

折射率

n20/D 1.430 (lit.)

pH值(酸碱度)

6.7

bp

153 °C (lit.)

mp

−61 °C (lit.)

密度

0.944 g/mL (lit.)

SMILES字符串

[H]C(=O)N(C)C

InChI

1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3

InChI key

ZMXDDKWLCZADIW-UHFFFAOYSA-N

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一般描述

N,N-Dimethylformamide (DMF) is an amide that works as a multipurpose reagent that is an effective polar solvent for various compounds and a ligand for metallic compounds. It also acts as a key intermediate as an electrophilic or nucleophilic agent for mediating reactions as it delivers its own H, C, N, and O atoms in compound synthesis.

应用

DMF is a widely used polar solvent in which organic, organometallic, and bioorganic transformations are carried out. It is also a solvent for many hydrophobic organic compounds and acts as a source of building blocks in various organic synthesis reactions.
多种疏水性有机化合物的溶剂。

警示用语:

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B

WGK

WGK 2

法规信息

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Recent Uses of N, N-Dimethylformamide and N, N-Dimethylacetamide as Reagents
Jean Le Bras, Jacques Muzart
Molecules (Basel), 23(8) (2018)
N,N-Dimethylformamide: much more than a solvent
Jacques Muzart
Tetrahedron, 65, 8313?8323-8313?8323 (2009)
A Journey from June 2018 to October 2021 with N, N-Dimethylformamide and N, N-Dimethylacetamide as Reactants
Jacques Muzart
Molecules (Basel), 26(21) (2021)

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