所有图片(3)
About This Item
经验公式（希尔记法）:
C6H6INO4
CAS号:
分子量:
283.02
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.22
推荐产品
产品名称
碘乙酸 N-羟基琥珀酰亚胺酯, powder
表单
powder
质量水平
反应适用性
reagent type: cross-linking reagent
溶解性
DMF: 50 mg/mL
应用
peptide synthesis
官能团
NHS ester
储存温度
−20°C
SMILES字符串
O=C(N1OC(CI)=O)CCC1=O
InChI
1S/C6H6INO4/c7-3-6(11)12-8-4(9)1-2-5(8)10/h1-3H2
InChI key
VRDGQQTWSGDXCU-UHFFFAOYSA-N
应用
具有氨基和巯基反应性的双异官能团交联剂。典型情况下，最初通过 pH 7.5 (6.5-8.5) 缓冲条件下的酰胺键偶联到含有伯胺的分子上，接着通过 pH 7.5 (7.0-8.0) 缓冲条件下的硫醚链与含有自由巯基的分子进行特异性次级键合。用于制备酶免疫交联剂和半抗原载体分子偶联物。提供两个原子的连接基。
注意
碘乙酰基具有光敏性。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Kevin Y Lin et al.
ACS nano, 7(10), 9001-9009 (2013-09-11)
Thrombin is a serine protease and regulator of hemostasis that plays a critical role in the formation of obstructive blood clots, or thrombosis, that is a life-threatening condition associated with numerous diseases such as atherosclerosis and stroke. To detect thrombi
Cody M Palumbo et al.
Chembiochem : a European journal of chemical biology, 21(11), 1633-1640 (2020-01-17)
Specific applications of CRISPR/Cas genome editing systems benefit from chemical modifications of the sgRNA. Herein we describe a versatile and efficient strategy for functionalization of the 3'-end of a sgRNA. An exemplary collection of six chemically modified sgRNAs was prepared
G Houen et al.
Journal of immunological methods, 181(2), 187-200 (1995-04-26)
Two methods for the preactivation of proteins and conjugation of peptides to proteins under mild conditions are presented. Preactivation of proteins with divinylsulfone (DVS) permits peptide conjugation through either amino, hydroxyl or sulphydryl groups depending on the coupling pH used
Jenny Tam et al.
International journal of molecular sciences, 21(9) (2020-05-01)
The use of fluorescent imaging probes that monitor the activity of proteases that experience an increase in expression and activity in tumors is well established. These probes can be conjugated to nanoparticles of iron oxide, creating a multimodal probe serving
Julian P Sefrin et al.
Frontiers in immunology, 10, 1962-1962 (2019-09-27)
Anti-tumor immunity is limited by a number of factors including the lack of fully activated T-cells, insufficient antigenic stimulation and the immune-suppressive tumor microenvironment. We addressed these hurdles by developing a novel class of immunoconjugates, Antibody-Targeted Pathogen-derived Peptides (ATPPs), which
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