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Merck
CN

H53704

Sigma-Aldrich

N-羟基邻苯二甲酰亚胺

97%, for peptide synthesis

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别名:
2-Hydroxy-1H-isoindole-1,3(2H)-dione, 2-Hydroxyisoindole-1,3-dione, 2-Hydroxyphthalimide
经验公式(希尔记法):
C8H5NO3
CAS号:
分子量:
163.13
Beilstein:
131208
EC 号:
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

97%

形式

crystalline

反应适用性

reaction type: Addition Reactions

mp

233 °C (dec.) (lit.)

应用

peptide synthesis

SMILES字符串

ON1C(=O)c2ccccc2C1=O

InChI

1S/C8H5NO3/c10-7-5-3-1-2-4-6(5)8(11)9(7)12/h1-4,12H

InChI key

CFMZSMGAMPBRBE-UHFFFAOYSA-N

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应用

制备胺核苷,以用于偶联反应生成非阴离子反义寡聚核苷。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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Tetrahedron Letters, 33, 2645-2645 (1992)
H M Petrassi et al.
Organic letters, 3(1), 139-142 (2001-06-30)
[figure: see text] A novel route to aryloxyamines via the copper-mediated cross-coupling of N-hydroxyphthalimide and phenylboronic acids is reported. The reaction is mediated by selected copper(I) and (II) salts in the presence of pyridine and is tolerant of several functional
S Coseri et al.
Biomacromolecules, 10(8), 2294-2299 (2009-09-03)
The oxidation reaction of regenerated cellulose fibers mediated by N-hydroxyphthalimide (NHPI) and various cocatalysts at room temperature for different time intervals and various amounts of low concentration sodium hypochlorite solution has been investigated to produce oxidized cellulose (OC), a biocompatible
[Hydroxyphthalimide induced medicamentosa-like dermatitis in five patients].
Jian-fang Zou et al.
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 24(10), 625-625 (2006-11-14)
V Krishnakumar et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 71(1), 110-115 (2008-01-26)
Single crystals of N-hydroxyphthalimide (NHPH) were obtained from saturated aqueous solutions of methanol and acetonitrile by slow cooling method. The grown crystals were bright and transparent. From the crystal structure analysis it can be inferred that the crystal belongs to

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