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Merck
CN

H53704

N-羟基邻苯二甲酰亚胺

97%, for peptide synthesis

别名:

2-Hydroxy-1H-isoindole-1,3(2H)-dione, 2-Hydroxyisoindole-1,3-dione, 2-Hydroxyphthalimide

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关于此项目

经验公式(希尔记法):
C8H5NO3
化学文摘社编号:
分子量:
163.13
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
EC Number:
208-358-1
MDL number:
Beilstein/REAXYS Number:
131208
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产品名称

N-羟基邻苯二甲酰亚胺, 97%

InChI key

CFMZSMGAMPBRBE-UHFFFAOYSA-N

InChI

1S/C8H5NO3/c10-7-5-3-1-2-4-6(5)8(11)9(7)12/h1-4,12H

SMILES string

ON1C(=O)c2ccccc2C1=O

assay

97%

form

crystalline

reaction suitability

reaction type: Addition Reactions

mp

233 °C (dec.) (lit.)

application(s)

peptide synthesis

Quality Level

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Application

制备胺核苷,以用于偶联反应生成非阴离子反义寡聚核苷。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

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Tetrahedron Letters, 33, 2645-2645 (1992)
Application of a dual linker with a reference cleavage site to discover a new reaction between amines and N-hydroxyphthalimide.
Viktor Krchnák et al.
Journal of combinatorial chemistry, 7(4), 523-525 (2005-07-12)
Yuuki Amaoka et al.
The Journal of organic chemistry, 77(22), 9959-9969 (2012-11-02)
A direct conversion of C(sp(3))-H bonds to C(sp(3))-N bonds has been achieved by utilizing catalytic N-hydroxyphthalimide (NHPI) and stoichiometric dialkyl azodicarboxylate. NHPI functions as a precursor of the electron-deficient phthalimide N-oxyl radical (PINO) to abstract hydrogens, and dialkyl azodicarboxylate acts
Francesca D'Acunzo et al.
European journal of biochemistry, 269(21), 5330-5335 (2002-10-24)
To investigate how solubility and steric issues affect the laccase-catalysed oxidation of phenols, a series of oligomeric polyphenol compounds, having increasing size and decreasing solubility in water, was incubated with laccase. The extent of substrate conversion, and the nature of
Riyuan Lin et al.
Organic letters, 14(16), 4158-4161 (2012-08-03)
A metal-free N-hydroxyphthalimide (NHPI) catalyzed aerobic oxidative cleavage of olefins has been developed. Molecular oxygen is used as the oxidant and reagent for this oxygenation reaction. This methodology has prevented the use of toxic metals or overstoichiometric amounts of traditional

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