质量水平
检测方案
97%
mp
161-163 °C (lit.)
SMILES字符串
Oc1cccc2C(=O)C=CC(=O)c12
InChI
1S/C10H6O3/c11-7-4-5-9(13)10-6(7)2-1-3-8(10)12/h1-5,12H
InChI key
KQPYUDDGWXQXHS-UHFFFAOYSA-N
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应用
5-羟基-1,4-萘醌(胡桃醌)可作为起始材料用于合成:
胡桃醌还可在狄尔斯–阿尔德反应中作为亲双烯体合成各种C-芳基糖苷。
- 杀锥虫药。
- 他克林-萘醌杂合物,治疗阿茲海默症的潜力药物。
- 基于胡桃醌的电活性聚合物聚(5-羟基-1,4-萘醌-co-5-羟基-3-硫代醋酸-1,4-萘醌),用于DNA杂交的电化学检测。
- Ent-nocardione A,天然存在的酪氨酸磷酸酶抑制剂。
胡桃醌还可在狄尔斯–阿尔德反应中作为亲双烯体合成各种C-芳基糖苷。
警示用语:
Danger
危险声明
危险分类
Acute Tox. 3 Oral
WGK
WGK 3
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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2-and 3-substituted 1, 4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from trypanosoma c ruzi: synthesis and correlation between redox cycling activities and in vitro cytotoxicity.
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Multitarget drug design strategy: quinone-tacrine hybrids designed to block amyloid-β aggregation and to exert anticholinesterase and antioxidant effects.
Journal of medicinal chemistry, 57(20), 8576-8589 (2014)
Application of an Enyne Metathesis/Diels-Alder Cycloaddition Sequence: A New Versatile Approach to the Syntheses of C-Aryl Glycosides and Spiro-C-Aryl Glycosides.
Chemistry?A European Journal , 16(28), 8545-8556 (2010)
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