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质量水平
检测方案
≥98% (TLC)
颜色
white to off-white
溶解性
H2O: 100 mg/mL
SMILES字符串
NCCS(O)=O
InChI
1S/C2H7NO2S/c3-1-2-6(4)5/h1-3H2,(H,4,5)
InChI key
VVIUBCNYACGLLV-UHFFFAOYSA-N
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应用
牛磺酸已被用作受精培养基（Fertrodede白蛋白乳酸丙酮酸盐（TALP））的补充剂，该培养基可用于 体外 受精和胚胎发育评估。它也可用作H2S的清除剂。
生化/生理作用
亚牛磺酸，一种胱胺类似物，是牛磺酸合成的前体。它可以作为抗氧化剂和单线态氧清除剂，从而保护细胞免受氧化损伤。据报道，亚牛磺酸在维持和刺激精子活动以及体外受精和胚胎发育中起重要作用。
键合羟自由基的抗氧化剂。内源抑制性神经调质，受番木鳖碱和印防己毒阻碍。抑制 GABA 和 β-丙氨酸的 Na2+ 依赖性运输。是半胱氨酸的降解产物，也是牛磺酸的前体。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Hypotaurine protection on cell damage by singlet oxygen.
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Taurine 4, 157-162 (2002)
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Fertility and sterility, 43(2), 263-267 (1985-02-01)
Removal of cumulus may increase the chance of fertilization in patients with sperm antibodies, may facilitate fertilization in vitro with a small number of spermatozoa, and is necessary for microsurgical injection procedures in vitro. The aim of this study was
Protective effect of hypotaurine against oxidative stress-induced cytotoxicity in rat placental trophoblasts.
Nishimura T
Placenta, 36(6), 693-698 (2015)
Andrea Carenzo et al.
Cells, 9(8) (2020-08-07)
Oral premalignant lesions (OPLs) represent the most common oral precancerous conditions. One of the major challenges in this field is the identification of OPLs at higher risk for oral squamous cell cancer (OSCC) development, by discovering molecular pathways deregulated in
Ultrastructural and immunohistochemical characterization of the bovine epiblast.
Vejlsted M, et al.
Biology of Reproduction, 72(3), 678-686 (2005)
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