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文件

G7208

亚硫酸亚乙酯

Name: 亚硫酸亚乙酯
Brand: ALDRICH

98%

别名:

2-氧代-1,3,2-二氧硫杂戊烷, ES, 乙二醇亚硫酸盐, 环亚乙基亚硫酸盐

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About This Item

经验公式（希尔记法）:

C₂H₄O₃S

CAS号:

3741-38-6

分子量:

108.12

Beilstein:

1237109

EC 号:

223-131-7

MDL编号:

MFCD00005354

UNSPSC代码:

12352100

PubChem化学物质编号:

24895296

NACRES:

NA.22

质量水平

200

检测方案

98%

形式

liquid

折射率

n20/D 1.445 (lit.)

bp

159.1 °C (lit.)

密度

1.426 g/mL at 25 °C (lit.)

SMILES字符串

O=S1OCCO1

InChI

1S/C2H4O3S/c3-6-4-1-2-5-6/h1-2H2

InChI key

WDXYVJKNSMILOQ-UHFFFAOYSA-N

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WGK

WGK 3

闪点(°F)

197.1 °F

闪点(°C)

91.7 °C

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Lipidic dispersion to reduce food dependent oral bioavailability of fenofibrate: In vitro, in vivo and in silico assessments.

Joseph P O'Shea et al.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 207-216 (2015-07-29)

Novel formulations that overcome the solubility limitations of poorly water soluble drugs (PWSD) are becoming ever more critical to a drug development process inundated with these compounds. There is a clear need for developing bio-enabling formulation approaches to improve oral

Development of novel docetaxel phospholipid nanoparticles for intravenous administration: quality by design approach.

Dharmendra K Yadav et al.

AAPS PharmSciTech, 16(4), 855-864 (2015-01-15)

The objective of this study was to develop novel docetaxel phospholipid nanoparticles (NDPNs) for intravenous administration. Modified solvent diffusion-evaporation method was adopted in the NDPN preparation. Central composite design (CCD) was employed in the optimization of the critical formulation factor

Lipid-based formulations solidified via adsorption onto the mesoporous carrier Neusilin® US2: effect of drug type and formulation composition on in vitro pharmaceutical performance.

Hywel D Williams et al.

Journal of pharmaceutical sciences, 103(6), 1734-1746 (2014-04-18)

The current study determined the extent to which the desorption of lipid-based formulations (LBFs) from a mesoporous magnesium aluminometasilicate (Neusilin®-US2) carrier is governed by drug properties, LBF composition, and LBF-to-adsorbent ratio. A secondary objective was to evaluate the impact of

Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4: proposing a new lipid formulation performance classification system.

Hywel D Williams et al.

Journal of pharmaceutical sciences, 103(8), 2441-2455 (2014-07-06)

The Lipid Formulation Classification System Consortium looks to develop standardized in vitro tests and to generate much-needed performance criteria for lipid-based formulations (LBFs). This article highlights the value of performing a second, more stressful digestion test to identify LBFs near

'Stealth' lipid-based formulations: poly(ethylene glycol)-mediated digestion inhibition improves oral bioavailability of a model poorly water soluble drug.

Orlagh M Feeney et al.

Journal of controlled release : official journal of the Controlled Release Society, 192, 219-227 (2014-07-25)

For over 20years, stealth drug delivery has been synonymous with nanoparticulate formulations and intravenous dosing. The putative determinants of stealth in these applications are the molecular weight and packing density of a hydrophilic polymer (commonly poly(ethylene glycol) (PEG)) that forms

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