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质量水平
检测方案
95%
mp
242-244 °C (dec.) (lit.)
SMILES字符串
NC(=N)Nc1nc2ccccc2[nH]1
InChI
1S/C8H9N5/c9-7(10)13-8-11-5-3-1-2-4-6(5)12-8/h1-4H,(H5,9,10,11,12,13)
InChI key
JJWCTKUQWXYIIU-UHFFFAOYSA-N
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Voltage-gated proton channels from fungi highlight role of peripheral regions in channel activation.
Chang Zhao et al.
Communications biology, 4(1), 261-261 (2021-02-28)
Here, we report the identification and characterization of the first proton channels from fungi. The fungal proteins are related to animal voltage-gated Hv channels and are conserved in both higher and lower fungi. Channels from Basidiomycota and Ascomycota appear to
S Friis et al.
The Journal of membrane biology, 184(3), 291-297 (2002-03-14)
In this communication we show that Gd3+ acts as an activator of the apical sodium channel (ENaC) in frog skin epithelia. Application of Gd3+ to the apical solution of frog skin epithelia increased the Na+ absorption measured as the amiloride-inhibitable
P Komwatana et al.
The Journal of membrane biology, 162(3), 225-232 (1998-05-16)
We have previously shown that epithelial Na+ channels in mouse mandibular gland duct cells are controlled by cytosolic Na+ and Cl-, acting, respectively, via Go and Gi proteins. Since we found no evidence for control of epithelial Na+ channels by
A Pinelli et al.
Arzneimittel-Forschung, 34(8), 890-894 (1984-01-01)
In this study 2-guanidinebenzimidazole (GBI) and 1-phenylbiguanide (PBG) appear to be capable of decreasing gastric acid secretion, while the compounds dimethylbiguanide and cyanoguanidine do not. Thus, the antisecretory effect is present when the biguanide groups are associated with lipophilic molecules.
K Eskesen et al.
Acta physiologica Scandinavica, 136(4), 547-550 (1989-08-01)
Serosal amiloride inhibits Na+, K+ and Cl- efflux and reduces short-circuit current and transepithelial conductance in noradrenaline-stimulated frog skin in which the sodium channels in the apical membrane are blocked by amiloride. BIG (benzimidazoleguanidine) inhibits Na+ and K+ efflux and
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