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经验公式(希尔记法):
C8H9NO2
化学文摘社编号:
分子量:
151.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-370-7
Beilstein/REAXYS Number:
122937
MDL number:
Assay:
99%
Form:
liquid
InChI
1S/C8H9NO2/c1-2-11-8(10)7-4-3-5-9-6-7/h3-6H,2H2,1H3
InChI key
XBLVHTDFJBKJLG-UHFFFAOYSA-N
SMILES string
CCOC(=O)c1cccnc1
assay
99%
form
liquid
Quality Level
bp
223-224 °C (lit.)
mp
8-10 °C (lit.)
density
1.107 g/mL at 25 °C (lit.)
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
target_organs
Respiratory system
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
199.4 °F - closed cup
flash_point_c
93 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Tanasait Ngawhirunpat et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 58(3), 645-651 (2004-09-29)
The skin transport and metabolism characteristics of ethyl nicotinate (EN) in rabbit, rat, guinea-pig, pig, shed snake skin and human were compared. In vitro skin transport using excised skin and hydrolysis experiments using skin homogenate were carried out. Flux of
Kenji Sugibayashi et al.
Drug metabolism and pharmacokinetics, 19(5), 352-362 (2004-11-19)
The simultaneous diffusion and metabolism of ethyl nicotinate (EN) in a cultured human skin model, Living Skin Equivalent-high, was evaluated by the in vitro skin permeation and metabolism experiments, and esterase distribution was also determined. Theoretical calculations using Fick's 2nd
Ibrahim Uçar et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 72(1), 11-16 (2008-11-18)
Mononuclear copper(II) saccharinate (sac) complex containing ethylnicotinate (enc), [Cu(enc)(2)(sac)(2)(H(2)O)].1.4H(2)O has been synthesized and characterized by spectroscopic (IR, UV-vis, EPR), X-ray diffraction technique and electrochemical methods. It crystallizes in the tetragonal crystal systems with space group I4(1)cd and Z=8. The copper(II)
K Sugibayashi et al.
Journal of controlled release : official journal of the Controlled Release Society, 62(1-2), 201-208 (1999-10-16)
An in vitro permeation study of ethyl nicotinate (EN) was carried out using excised hairless rat skin, and simultaneous skin transport and metabolism of the drug were kinetically followed. Fairly good steady-state fluxes of EN and its metabolite nicotinic acid
T Ngawhirunpat et al.
Biological & pharmaceutical bulletin, 24(4), 414-417 (2001-04-18)
The age-dependent characteristics of transdermal permeation of ethyl nicotinate (EN) and its metabolism to nicotinic acid (NA) were examined in rats at the ages of a fetus at 21 d, 3, 10, 50, 270 and 360 d. Skin transport in
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