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Merck
CN

D98807

Sigma-Aldrich

N,N-二乙基烟酰胺

99%

别名:

DENC, `尼可刹米', 烟酸二乙胺

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About This Item

经验公式(希尔记法):
C10H14N2O
CAS号:
分子量:
178.23
Beilstein:
5743
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

99%

表单

liquid

折射率

n20/D 1.524 (lit.)

沸点

296-300 °C (lit.)

mp

23 °C (lit.)

密度

1.06 g/mL at 25 °C (lit.)

SMILES字符串

CCN(CC)C(=O)c1cccnc1

InChI

1S/C10H14N2O/c1-3-12(4-2)10(13)9-6-5-7-11-8-9/h5-8H,3-4H2,1-2H3

InChI key

NCYVXEGFNDZQCU-UHFFFAOYSA-N

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应用

N,N-二乙基烟酰胺(DENC)常用作制备四核铜配合物的配体。

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral - Eye Irrit. 2

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

闪点(°F)

235.4 °F - closed cup

闪点(°C)

113 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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分析证书(COA)

Lot/Batch Number

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Synthesis, structure and properties of the tetranuclear complexes [(DENC) CuX] 4 (DENC= N, N-diethylnicotinamide; X= Cl, Br, I) and the kinetics of oxidation of the chloride and bromide by dioxygen in aprotic solvents.
Churchill M R, et al.
Inorganic Chemistry, 21(3), 995-1001 (1982)
Transmetalation reactions of tetranuclear copper (II) complexes. 2. Stoichiometry and products of reaction of [(DENC) CuCl] 4O2,[(DENC) CuCl] 4 (CO3) 2,[(DENC) CuCl] 4Cl4, and (DENC) 4Cu4Cl6O (DENC= N, N-diethylnicotinamide) with Ni (NS) 2, the kinetics of product isomerization in aprotic solvents, and inhibition of copper-catalyzed phenolic. oxidativecoupling by dioxygen through transmetalation.
El-Toukhy A, et al.
Journal of the American Chemical Society, 106(16), 4596-4605 (1984)
Synthesis and properties of mixed-valence copper molecules (. mu.-Y) N4CuII2CUI2X4 (N= N, N-diethylnicotinamide; Y= 3, 4, 5, 6-tetrachlorocatecholate; X= Cl, Br, I) and the products and kinetics of their reactions with dioxygen and nitrobenzene.
El-Sayed M A and Davies G
Inorganic Chemistry, 29(24), 4891-4897 (1990)
Tooru Ooya et al.
Journal of controlled release : official journal of the Controlled Release Society, 93(2), 121-127 (2003-11-26)
New methods and pharmaceutical compositions were developed to increase the aqueous solubility of paclitaxel (PTX), a poorly water-soluble drug. Graft and star-shaped graft polymers consisting of poly(ethylene glycol) (PEG400) graft chains increased the PTX solubility in water by three orders
Namjin Baek et al.
Journal of biomaterials science. Polymer edition, 15(4), 527-542 (2004-06-24)
N,N-Diethylnicotinamide (DENA) was identified as an excellent hydrotropic agent for paclitaxel (PTX) in our previous studies. The aqueous solubility of PTX was increased by several orders of magnitude in the presence of DENA. Because of such a high hydrotropic property

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