D7631
5,5-二甲基噁唑烷-2,4-二酮
别名:
DMO, NSC 30152, 二甲双酮
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关于此项目
经验公式（希尔记法）:
C5H7NO3
化学文摘社编号:
分子量:
129.11
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
211-781-4
MDL number:
Form:
powder
InChI key
JYJFNDQBESEHJQ-UHFFFAOYSA-N
InChI
1S/C5H7NO3/c1-5(2)3(7)6-4(8)9-5/h1-2H3,(H,6,7,8)
SMILES string
CC1(C)OC(=O)NC1=O
form
powder
mp
77-80 °C (lit.)
storage temp.
2-8°C
Quality Level
Application
作为反应物，参与以下反应：
参与药理学研究的分子包括：
- 苯并环镍或萘环镍β氧杂氮杂氯配合物的合成
- 用作组织蛋白酶K抑制剂
参与药理学研究的分子包括：
- 抗癫痫药生物等效仿制药的鉴定
- 筛选将能量代谢从线粒体呼吸转变为糖酵解的药物
- 溶解总胆管囊肿/胰胆管连接不良患者的蛋白塞
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
D P Nolan et al.
European journal of biochemistry, 267(15), 4601-4614 (2000-07-21)
Conditions for the use of both [14C]methylamine and 5, 5-dimethyl[14C]oxa-azolidine-2,4-dione (DMO) to measure the H+ concentration of intracellular compartments of monomorphic long thin bloodstream forms of Trypanosoma brucei were established. Neither probe was actively transported or bound to internal components
Christian Danielsson et al.
Birth defects research. Part A, Clinical and molecular teratology, 79(8), 595-603 (2007-06-23)
The antiepileptic drugs (AEDs) phenytoin, phenobarbital, dimethadione, and carbamazepine cause a similar pattern of malformations in humans, with an increased risk after polytherapy. The teratogenicity has been linked to cardiac rhythm disturbances and hypoxic damage as a consequence of their
Jingxuan Wang et al.
Food & function, 10(8), 4823-4833 (2019-07-19)
Donkey milk is considered to be a valuable nutritional source. Deeper knowledge of the constituents of donkey milk is necessary. As multifunctional components of milk, oligosaccharides have been reported to have the potential to support intestine development. We studied the
Anne C Biechl et al.
Clinical & experimental ophthalmology, 48(6), 802-812 (2020-05-10)
Evaluating the treatment outcomes of diabetic macular oedema (DMO) in routine clinical practice provides data for comparison with those of clinical trials. Phase 3 clinical trials of vascular endothelial growth factor (VEGF) inhibitors for DMO have reported significant improvements in
D P Nolan et al.
European journal of biochemistry, 267(1), 18-27 (1999-12-22)
Natural infections of mammals with African trypanosomes, such as Trypanosoma brucei, are generally pleomorphic, the population consisting of different forms, termed slender and stumpy forms, that vary in number as the parasitaemia develops. We show that the differentiation of slender
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