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Merck
CN

D70406

Sigma-Aldrich

3,4-二氯苯酚

99%

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别名:
3,4-DCP
线性分子式:
Cl2C6H3OH
CAS号:
分子量:
163.00
Beilstein:
1907693
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

99%

形式

crystals

bp

~253 °C (lit.)

mp

65-67 °C (lit.)

SMILES字符串

Oc1ccc(Cl)c(Cl)c1

InChI

1S/C6H4Cl2O/c7-5-2-1-4(9)3-6(5)8/h1-3,9H

InChI key

WDNBURPWRNALGP-UHFFFAOYSA-N

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应用

3,4-二氯苯酚(3,4-DCP)可用于合成(Z)-5-芳基亚甲基罗丹宁,其可作为抗甲氧西林 金黄色葡萄球菌 (MRSA)的抗性试剂。 它也可用于制备2-(3,4-二氯苯氧基)-N-(2-吗啉-4-基乙基)乙酰胺,其可用于治疗炎性疼痛。

象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

危险化学品

分析证书(COA)

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The synthesis and SAR study of phenylalanine-derived (Z)-5-arylmethylidene rhodanines as anti-methicillin-resistant Staphylococcus aureus (MRSA) compounds.
Patel BA, et al.
Bioorganic & Medicinal Chemistry Letters, 23(20), 5523-5527 (2013)
Discovery of 2-(3, 4-dichlorophenoxy)-N-(2-morpholin-4-ylethyl) acetamide: A selective ?1 receptor ligand with antinociceptive effect.
Navarrete-Vazquez G, et al.
Biomedicine and Pharmacotherapy, 79(20), 284-293 (2016)
J H Carey et al.
Canadian journal of physiology and pharmacology, 62(8), 971-975 (1984-08-01)
The disappearance rates of 2,4- and 3,4-dichlorophenol in a small stream were studied and were shown to be first order with respect to either distance or time of flow. Both chlorophenols disappeared at approximately the same rate with average half-lives
F O Bryant et al.
Applied and environmental microbiology, 57(8), 2293-2301 (1991-08-01)
The reductive dechlorination of pentachlorophenol (PCP) was investigated in anaerobic sediments that contained nonadapted or 2,4- or 3,4-dichlorophenol (DCP)-adapted microbial communities. Adaptation of sediment communities increased the rate of conversion of 2,4- or 3,4-DCP to monochlorophenols (CPs) and eliminated the
Julien Michel et al.
Journal of the American Chemical Society, 131(18), 6356-6357 (2009-05-07)
There is great interest in molecules capable of inhibiting the interactions between p53 and its negative regulators hDM2 and hDMX, as these molecules have validated potential against cancers in which one or both oncoproteins are overexpressed. We reported previously that

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