检测方案
97%
形式
solid
bp
258 °C (lit.)
mp
29-32 °C (lit.)
SMILES字符串
[O-][N+](=O)c1ccc(Cl)cc1Cl
InChI
1S/C6H3Cl2NO2/c7-4-1-2-6(9(10)11)5(8)3-4/h1-3H
InChI key
QUIMTLZDMCNYGY-UHFFFAOYSA-N
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警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1B - Muta. 2 - Skin Sens. 1B
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
V Breinholt et al.
Cancer letters, 154(2), 201-210 (2000-05-12)
The administration of lycopene to female rats at doses ranging from 0.001 to 0.1 g/kg b.w. per day for 2 weeks was found to alter the drug-metabolizing capacity and antioxidant status of the exposed animals. An investigation of four cytochrome
Bruno Miguel Neves et al.
Toxicology letters, 177(1), 74-82 (2008-02-19)
The development of non-animal methods for skin sensitization testing is an urgent challenge. Some of the most promising in vitro approaches are based on the analysis of phenotypical and functional modifications induced by sensitizers in dendritic cell models. In this
Maja Aleksic et al.
Toxicology in vitro : an international journal published in association with BIBRA, 21(4), 723-733 (2007-02-24)
Covalent modification of skin proteins by electrophiles is a key event in the induction of skin sensitisation but not skin irritation although the exact nature of the binding mechanisms has not been determined empirically for the vast majority of sensitisers.
P A Botham et al.
The British journal of dermatology, 117(1), 1-9 (1987-07-01)
The fate of 2,4-dinitrochlorobenzene, a potent contact sensitizing chemical, and 2,4-dichloronitrobenzene, a non-sensitizer, was compared following their application to the skin of BALB/c mice. Although both chemicals were able to bind to protein in vitro and were capable of being
Makoto Ohnishi et al.
The Journal of toxicological sciences, 34(2), 233-237 (2009-04-02)
Oral administration of 2,4-dichloro-1-nitrobenzene (2,4-DCNB) causes kidney tumors in the rat. The objective of the present study was to identify the chemical structure of 2,4-DCNB metabolites in urine. Urine from 2,4-DCNB fed rats was more yellow than urine from control
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