D55008
二氯乙酰氯
98%
别名:
α,α-二氯乙酰氯, 二氯乙酰氯
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关于此项目
线性分子式:
Cl2CHCOCl
化学文摘社编号:
分子量:
147.39
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-199-9
Beilstein/REAXYS Number:
1209426
MDL number:
产品名称
二氯乙酰氯, 98%
InChI key
FBCCMZVIWNDFMO-UHFFFAOYSA-N
InChI
1S/C2HCl3O/c3-1(4)2(5)6/h1H
SMILES string
ClC(Cl)C(Cl)=O
assay
98%
form
liquid
refractive index
n20/D 1.46 (lit.)
bp
107-108 °C (lit.)
density
1.532 g/mL at 25 °C (lit.)
Quality Level
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signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Carc. 1B - Eye Dam. 1 - Skin Corr. 1A
supp_hazards
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
Rolf König et al.
Chemical research in toxicology, 21(3), 572-582 (2008-02-26)
Dichloroacetyl chloride (DCAC) is a reactive metabolite of trichloroethene (TCE). TCE and its metabolites have been implicated in the induction of organ-specific and systemic autoimmunity, in the acceleration of autoimmune responses, and in the development of liver toxicity and hepatocellular
M F Khan et al.
Immunopharmacology and immunotoxicology, 19(2), 265-277 (1997-05-01)
Welders are exposed to dichloroacetyl chloride (DCAC) when trichloroethene (TCE) is used as a degreasing agent. Human exposure to TCE and tetrachloroethane can also lead to formation of DCAC in situ through metabolism. Due to its strong acylating property, it
Hsin-Hung Ou et al.
Journal of hazardous materials, 146(1-2), 302-308 (2007-01-24)
Batch photocatalytic degradation of 80+/-2.5 ppm V trichloroethylene (TCE) was conducted to investigate the effect of the oxygen and relative humidity (RH) on the formation of the dichloroacetyl chloride (DCAC) and phosgene. Based on the simultaneous ordinary differential equations (ODEs)
M F Khan et al.
Toxicology and applied pharmacology, 170(2), 88-92 (2001-02-13)
Trichloroethene (TCE) and one of its metabolites dichloroacetyl chloride (DCAC) are known to induce/accelerate autoimmune (AI) response in MRL+/+ mice as evident from anti-nuclear, anti-ssDNA, anti-cardiolipin, and DCAC-specific antibodies in the serum (Khan et al., Toxicol. Appl. Pharmacol. 134, 155-160
A R Sellakumar et al.
Journal of the National Cancer Institute, 79(2), 285-289 (1987-08-01)
A series of earlier studies showed that inhalation exposures of rats to three water-reactive electrophilic compounds produced brisk yields of nasal cancer even when the animals were exposed for only 30 days (6 hr/day X 5 day/wk). In addition, carcinogenic
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