推荐产品
质量水平
检测方案
≥98%
形式
powder
储存温度
−20°C
SMILES字符串
OC(=O)CSSCC(O)=O
InChI
1S/C4H6O4S2/c5-3(6)1-9-10-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)
InChI key
DLLMHEDYJQACRM-UHFFFAOYSA-N
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应用
- Enhancement of octacalcium phosphate via Dithiodiglycolic acid: Research on the interlayer expansion of octacalcium phosphate illustrates the forced oxidation of Dithiodiglycolic acid intercalated molecules within its interlayers, showcasing a novel application in material science and chemical engineering (Sugiura et al., 2023).
- Drug delivery systems: A study on redox-responsive self-assembly PEG nanoparticles enhanced by triptolide, where Dithiodiglycolic acid plays a critical role, demonstrates its potential in improving the efficacy of antitumor treatments, providing insights into pharmaceutical applications (Wang et al., 2018).
- Synthesis and medicinal applications: A comprehensive study on the synthesis and biological evaluation of Dithiodiglycolic acid derivatives via oxidative coupling of thiols highlights its utility in medicinal chemistry, offering new avenues for drug design and development (Bakulina et al., 2019).
- Redox-sensitive coordination polymers: The development of redox-sensitive nanoscale coordination polymers for drug delivery and cancer theranostics utilizes Dithiodiglycolic acid, providing significant advancements in cancer treatment strategies (Zhao et al., 2017).
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Shenwu Zhang et al.
Drug delivery, 24(1), 1460-1469 (2017-09-28)
Breast cancer leads to high mortality of women in the world. Docetaxel (DTX) has been widely applied as one of the first-line chemotherapeutic drugs for breast cancer therapy. However, the clinical outcome of DTX is far from satisfaction due to
Huiyun Zhang et al.
Drug development and industrial pharmacy, 46(11), 1800-1808 (2020-09-25)
Curcumin (CUR), a nontoxic natural compound with potent antitumor activity, was limited in clinical application due to its insolubility and exceedingly low bioavailability. In this study, a novel prodrug-nanoparticle (CSSV/TPGS-NPs) self-assembled by co-nanoprecipitation of CUR-s-s-vitamin E conjugate and d-alpha-tocopheryl polyethylene
Huiyun Zhang et al.
International journal of pharmaceutics, 575, 118980-118980 (2020-01-04)
Cardiac glycosides (CGs) have been used to treat cancer for hundreds of years. However, the narrow therapeutic window and system toxicity have hindered their wide clinical applications. Herein, the small molecule prodrug strategy and nanotechnology were integrated into one drug
Hui-Yun Zhang et al.
International journal of pharmaceutics, 555, 270-279 (2018-11-25)
The anti-tumor efficacy of curcumin can be markedly improved by nano-drug self-delivery systems with high drug loading capacity and smart stimulus-triggered drug release in tumor cells. Herein, a type of novel, glutathione (GSH)-responsive, PEGylated prodrug nano-micelles (PPNMs) was prepared by
Huiyun Zhang et al.
Drug delivery, 24(1), 1170-1178 (2017-08-25)
Periplocymarin (PPM), a cardiac glycoside, has a narrow therapeutic index, poor tumor selectivity and severe cardiovascular toxicity which hinder its wide clinical applications in cancer treatment. Herein, we report novel redox-responsive prodrug-nanoparticles (MPSSV-NPs) self-assembled by co-nanoprecipitation of PPM-vitamin E conjugate
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