D3511
反式-4,5-二羟基-1,2-二噻烷
≥99%
别名:
反式-1,2-二噻烷-4,5-二醇, 氧化 DTT
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关于此项目
经验公式（希尔记法）:
C4H8O2S2
化学文摘社编号:
分子量:
152.24
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
238-047-6
MDL number:
产品名称
反式-4,5-二羟基-1,2-二噻烷, ≥99%
InChI key
YPGMOWHXEQDBBV-QWWZWVQMSA-N
InChI
1S/C4H8O2S2/c5-3-1-7-8-2-4(3)6/h3-6H,1-2H2/t3-,4-/m1/s1
SMILES string
O[C@@H]1CSSC[C@H]1O
assay
≥99%
form
powder
greener alternative product score
old score: 9
new score: 6
Find out more about DOZN™ Scoring
greener alternative product characteristics
Atom Economy
Less Hazardous Chemical Syntheses
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
mp
130-132 °C (lit.)
greener alternative category
storage temp.
2-8°C
Quality Level
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General description
反式 -4,5-二羟基-1,2-二噻烷（氧化 dtt）是二硫苏糖醇的分子内二硫键形式。它是一种强还原剂，能够通过激活应激反应基因引发分子应激反应。
我们竭诚为您带来满足绿色替代产品四大类别要求的替代产品。该产品属于再设计产品类别，在“原子经济性”、“危险性较小的化学合成”和“使用可再生原料”绿色化学原则方面取得了重大改进。 点击此处查看其 DOZN 记分卡。
Other Notes
二硫苏糖醇 (DTT) 的氧化型。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Reduction of trans-4, 5-Dihydroxy-1, 2-dithiane by Cellular Oxidoreductases Activates gadd153/chop and grp78 Transcription and Induces Cellular Tolerance in Kidney Epithelial Cells.
Halleck MM
The Journal of Biological Chemistry, 272(35), 21760-21766 (1997)
Jing Li et al.
PloS one, 12(2), e0172504-e0172504 (2017-02-23)
Starch breakdown in leaves at night is tightly matched to the duration of the dark period, but the mechanism by which this regulation is achieved is unknown. In Arabidopsis chloroplasts, β-amylase BAM3 hydrolyses transitory starch, producing maltose and residual maltotriose.
Francesca Sparla et al.
Plant physiology, 141(3), 840-850 (2006-05-16)
Nine genes of Arabidopsis (Arabidopsis thaliana) encode for beta-amylase isozymes. Six members of the family are predicted to be extrachloroplastic isozymes and three contain predicted plastid transit peptides. Among the latter, chloroplast-targeted beta-amylase (At4g17090) and thioredoxin-regulated beta-amylase (TR-BAMY; At3g23920; this
Hélène Launay et al.
Journal of molecular biology, 430(8), 1218-1234 (2018-03-05)
Among intrinsically disordered proteins, conditionally disordered proteins undergo dramatic structural disorder rearrangements upon environmental changes and/or post-translational modifications that directly modulate their function. Quantifying the dynamics of these fluctuating proteins is extremely challenging but paramount to understanding the regulation of
Modulating the endoplasmic reticulum stress response with trans-4, 5-dihydroxy-1, 2-dithiane prevents chemically induced renal injury in vivo.
Asmellash S
Toxicological Sciences, 88(2), 576-584 (2005)
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