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Merck
CN

D3511

Sigma-Aldrich

反式-4,5-二羟基-1,2-二噻烷

greener alternative

≥99%

别名:

反式-1,2-二噻烷-4,5-二醇, 氧化 DTT

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About This Item

经验公式(希尔记法):
C4H8O2S2
CAS号:
分子量:
152.24
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

≥99%

表单

powder

环保替代产品得分

old score: 9
new score: 6
Find out more about DOZN™ Scoring

环保替代产品特性

Atom Economy
Less Hazardous Chemical Syntheses
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

130-132 °C (lit.)

环保替代产品分类

储存温度

2-8°C

SMILES字符串

O[C@@H]1CSSC[C@H]1O

InChI

1S/C4H8O2S2/c5-3-1-7-8-2-4(3)6/h3-6H,1-2H2/t3-,4-/m1/s1

InChI key

YPGMOWHXEQDBBV-QWWZWVQMSA-N

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相关类别

一般描述

反式 -4,5-二羟基-1,2-二噻烷(氧化 dtt)是二硫苏糖醇的分子内二硫键形式。它是一种强还原剂,能够通过激活应激反应基因引发分子应激反应。
我们竭诚为您带来满足绿色替代产品四大类别要求的替代产品。该产品属于再设计产品类别,在“原子经济性”、“危险性较小的化学合成”和“使用可再生原料”绿色化学原则方面取得了重大改进。 点击此处查看其 DOZN 记分卡。

联系

二硫苏糖醇 (DTT) 的氧化型。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

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访问文档库

Jing Li et al.
PloS one, 12(2), e0172504-e0172504 (2017-02-23)
Starch breakdown in leaves at night is tightly matched to the duration of the dark period, but the mechanism by which this regulation is achieved is unknown. In Arabidopsis chloroplasts, β-amylase BAM3 hydrolyses transitory starch, producing maltose and residual maltotriose.
Reduction of trans-4, 5-Dihydroxy-1, 2-dithiane by Cellular Oxidoreductases Activates gadd153/chop and grp78 Transcription and Induces Cellular Tolerance in Kidney Epithelial Cells.
Halleck MM
The Journal of Biological Chemistry, 272(35), 21760-21766 (1997)
Zimai Li et al.
Antioxidants (Basel, Switzerland), 9(10) (2020-10-18)
Reactive sulfane sulfur, including persulfide and polysulfide, is a type of regular cellular component, playing an antioxidant role. Its function may be organelle-dependent; however, the shortage of probes for detecting organellar reactive sulfane sulfur has hindered further investigation. Herein, we
Modulating the endoplasmic reticulum stress response with trans-4, 5-dihydroxy-1, 2-dithiane prevents chemically induced renal injury in vivo.
Asmellash S
Toxicological Sciences, 88(2), 576-584 (2005)
Hélène Launay et al.
Journal of molecular biology, 430(8), 1218-1234 (2018-03-05)
Among intrinsically disordered proteins, conditionally disordered proteins undergo dramatic structural disorder rearrangements upon environmental changes and/or post-translational modifications that directly modulate their function. Quantifying the dynamics of these fluctuating proteins is extremely challenging but paramount to understanding the regulation of

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