D2388
3,3′-二硫代双丙亚氨酸二甲酯 二盐酸盐
powder
别名:
3,3′-二硫代丙亚氨酸二甲酯 二盐酸盐, DTBP, Wang/Richards 试剂
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C8H16N2O2S2 · 2HCl
化学文摘社编号:
分子量:
309.28
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352116
MDL number:
Form:
powder
InChI
1S/C8H16N2O2S2.2ClH/c1-11-7(9)3-5-13-14-6-4-8(10)12-2;;/h9-10H,3-6H2,1-2H3;2*1H
SMILES string
Cl.Cl.COC(=N)CCSSCCC(=N)OC
InChI key
CQBCVFHLZAVNPF-UHFFFAOYSA-N
form
powder
reaction suitability
reagent type: cross-linking reagent
solubility
H2O: 50 mg/mL
storage temp.
2-8°C
Application
作为以下反应的反应物：
- 合成谷胱甘肽敏感的交联聚乙烯亚胺基因载体
- 制备用于基因递送的含环糊精聚合物
- 交联鸡输卵管孕激素受体亚基
同源双功能、可裂解交联试剂。通常，与伯胺在 pH 7.0-10.0 范围内反应形成脒键。
Other Notes
注意：脒键具有初始伯胺的正电荷。可由轻度还原反应裂解二硫键。含有一个八原子连接基。
Disclaimer
该试剂在中性 pH 下易水解。在偶联反应时应避免使用还原剂。
John G Lock et al.
Nature cell biology, 20(11), 1290-1302 (2018-10-27)
Adhesion to the extracellular matrix persists during mitosis in most cell types. However, while classical adhesion complexes, such as focal adhesions, do and must disassemble to enable mitotic rounding, the mechanisms of residual mitotic cell-extracellular matrix adhesion remain undefined. Here
Carine F Djuika et al.
Scientific reports, 7(1), 4410-4410 (2017-07-02)
Artemisinins are the current mainstay of malaria chemotherapy. Their exact mode of action is an ongoing matter of debate, and several factors have recently been reported to affect an early stage of artemisinin resistance of the most important human malaria
Choong Eun Jin et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 5(10), 1800614-1800614 (2018-10-26)
Cell-free nucleic acids (cfNAs) are emerging diagnostic biomarkers for monitoring the treatment and recurrence of cancers. In particular, the biological role and clinical usefulness of cfNAs obtained from the plasma of patients with various cancers are popular and still intensely
Lalit Yadav et al.
Organic & biomolecular chemistry, 18(30), 5927-5936 (2020-07-22)
A Bu4NI-catalyzed, DTBP-promoted, regioselective C(sp2)-C(sp3) cross dehydrogenative coupling (CDC) protocol for the direct C-3 benzylation of 2H-indazoles is reported. The metal-free protocol is operationally simple and proceeds mechanistically via the generation of stable benzylic free-radicals followed by regioselective addition at
K Satoh et al.
Biochemistry, 40(2), 314-319 (2001-01-10)
We investigated whether the assembly/disassembly of the 26S proteasome is regulated by phosphorylation/dephosphorylation. The regulatory complex disassembled from the 26S proteasome was capable of phosphorylating the p45/Sug1/Rpt6 subunit, suggesting that the protein kinase is activated upon dissociation of the 26S
商品
Kanjiro Miyata (The University of Tokyo, Japan) provides insights on the rational design of polymeric materials for “smart” oligonucleotide delivery.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持