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Merck
CN

D2388

Sigma-Aldrich

3,3′-二硫代双丙亚氨酸二甲酯 二盐酸盐

powder

别名:

3,3′-二硫代丙亚氨酸二甲酯 二盐酸盐, DTBP, Wang/Richards 试剂

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About This Item

经验公式(希尔记法):
C8H16N2O2S2 · 2HCl
CAS号:
分子量:
309.28
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.22

表单

powder

质量水平

反应适用性

reagent type: cross-linking reagent

溶解性

H2O: 50 mg/mL

储存温度

2-8°C

SMILES字符串

Cl.Cl.COC(=N)CCSSCCC(=N)OC

InChI

1S/C8H16N2O2S2.2ClH/c1-11-7(9)3-5-13-14-6-4-8(10)12-2;;/h9-10H,3-6H2,1-2H3;2*1H

InChI key

CQBCVFHLZAVNPF-UHFFFAOYSA-N

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应用

作为以下反应的反应物:
  • 合成谷胱甘肽敏感的交联聚乙烯亚胺基因载体
  • 制备用于基因递送的含环糊精聚合物
  • 交联鸡输卵管孕激素受体亚基

注意

该试剂在中性 pH 下易水解。在偶联反应时应避免使用还原剂。

其他说明

注意:脒键具有初始伯胺的正电荷。可由轻度还原反应裂解二硫键。含有一个八原子连接基。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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Organic & biomolecular chemistry, 18(30), 5927-5936 (2020-07-22)
A Bu4NI-catalyzed, DTBP-promoted, regioselective C(sp2)-C(sp3) cross dehydrogenative coupling (CDC) protocol for the direct C-3 benzylation of 2H-indazoles is reported. The metal-free protocol is operationally simple and proceeds mechanistically via the generation of stable benzylic free-radicals followed by regioselective addition at
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Scientific reports, 7(1), 4410-4410 (2017-07-02)
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K Satoh et al.
Biochemistry, 40(2), 314-319 (2001-01-10)
We investigated whether the assembly/disassembly of the 26S proteasome is regulated by phosphorylation/dephosphorylation. The regulatory complex disassembled from the 26S proteasome was capable of phosphorylating the p45/Sug1/Rpt6 subunit, suggesting that the protein kinase is activated upon dissociation of the 26S

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