C85778
邻甲酚酞
Indicator grade, powder
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关于此项目
经验公式（希尔记法）:
C22H18O4
化学文摘社编号:
分子量:
346.38
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
209-881-8
MDL number:
Beilstein/REAXYS Number:
310554
产品名称
邻甲酚酞, indicator grade
InChI
1S/C22H18O4/c1-13-11-15(7-9-19(13)23)22(16-8-10-20(24)14(2)12-16)18-6-4-3-5-17(18)21(25)26-22/h3-12,23-24H,1-2H3
InChI key
CPBJMKMKNCRKQB-UHFFFAOYSA-N
SMILES string
Cc1cc(ccc1O)C2(OC(=O)c3ccccc23)c4ccc(O)c(C)c4
grade
indicator grade
form
powder
technique(s)
titration: suitable
color
beige
pH
8.2-9.8, colorless to red
mp
219-221 °C (lit.)
λmax
381 nm (2nd)
566 nm
ε (extinction coefficient)
≥10000 at 294-300 nm
≥39000 at 564-570 nm
≥5000 at 378-384 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Quality Level
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Application
O -甲酚酞作为钙化介质中的组分用于钙化试验。
Biochem/physiol Actions
o -甲酚酞是一种可逆的 pH 指示剂。反向通路（红紫色至无色）的动力学是缓慢的，因此使其成为检查波纹壁管中流动模式的适当分子。也用于通过 o -甲酚酞络合酮方法比色测定钙含量。在碱性条件 (pH 10-12) 下，钙与 o -甲酚酞结合，形成红色复合物，在 570-575 nm 处有吸光度。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Handbook on Metals in Clinical and Analytical Chemistry (1994)
Diabetic vascular calcification mediated by the collagen receptor discoidin domain receptor 1 via the Phosphoinositide 3-Kinase/Akt/Runt-related transcription factor 2 signaling axis
Lino M, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 38(8), 1878-1889 (2018)
J E Van Nuwenborg et al.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 35(4), 297-300 (1997-04-01)
We evaluated bias and inaccuracy of four frequently used routine test systems for serum total calcium, using a candidate reference method based on ion chromatography. The mean biases and 95% confidence intervals that we observed were 0.0 +/- 0.59% for
Jin-Hyun Kim et al.
PloS one, 14(4), e0215244-e0215244 (2019-04-17)
In the stratum corneum, the intercellular junction made up of cadherin proteins provides the structural integrity of the framework. Ca2+ ions are known to play a key role in maintaining this junction. In this study, we hypothesized that Ca2+ chelation
Hyunseok Peter Kang et al.
Clinical chemistry, 50(4), 741-746 (2004-02-14)
Gadolinium formulations, which are administered as contrast agents in magnetic resonance imaging examinations, interfere with colorimetric serum calcium determinations. We performed an in vitro study to determine the extent to which three gadolinium formulations-gadodiamide (Omniscan), gadopentetate dimeglumine (Magnevist), and gadoversetamide
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