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质量水平
方案
95%
表单
crystals
反应适用性
reaction type: C-C Bond Formation
mp
128-130 °C (lit.)
储存温度
2-8°C
SMILES字符串
CCOC(=O)C=P(c1ccccc1)(c2ccccc2)c3ccccc3
InChI
1S/C22H21O2P/c1-2-24-22(23)18-25(19-12-6-3-7-13-19,20-14-8-4-9-15-20)21-16-10-5-11-17-21/h3-18H,2H2,1H3
InChI key
IIHPVYJPDKJYOU-UHFFFAOYSA-N
应用
乙氧甲酰基亚甲基三苯基膦是一种Horner-Wittig试剂,常用于 Horner−Wadsworth−Emmons(HWE)反应。它可用作 (−)-奥司他韦、 (+)-nakadomarin A和(−)-dictyostatin等化合物全合成的反应试剂。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
The first total synthesis of nakadomarin A
Journal of the American Chemical Society, 125(25), 7484-7485 (2003)
Total synthesis of (−)-dictyostatin
Journal of the American Chemical Society, 128(16), 5340-5341 (2006)
Nucleophilicity parameters for phosphoryl-stabilized carbanions and phosphorus ylides: Implications for wittig and related olefination reactions
Journal of the American Chemical Society, 131(2), 704-714 (2008)
Scope and limitation of the reactions of 3-imino derivatives of pentane-2, 4-diones with organophosphorus reagents
Phosphorus, Sulfur, and Silicon and the Related Elements, 187(6), 697-710 (2012)
High-yielding synthesis of the anti-influenza neuraminidase inhibitor (−)-oseltamivir by two ?one-pot? sequences
Chemistry?A European Journal , 16(42), 12616-12626 (2010)
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