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Merck
CN

C19686

2-Chloroacetophenone

98%

别名:

ω-Chloroacetophenone, Phenacyl chloride

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线性分子式:
C6H5COCH2Cl
化学文摘社编号:
分子量:
154.59
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-531-1
Beilstein/REAXYS Number:
507950
MDL number:
Assay:
98%
Form:
crystals
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InChI key

IMACFCSSMIZSPP-UHFFFAOYSA-N

InChI

1S/C8H7ClO/c9-6-8(10)7-4-2-1-3-5-7/h1-5H,6H2

SMILES string

ClCC(=O)c1ccccc1

assay

98%

form

crystals

bp

244-245 °C (lit.)

mp

54-56 °C (lit.)

density

1.324 g/mL at 25 °C (lit.)

Quality Level

Gene Information

human ... PTPN6(5777)

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signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Expanding the [1,2]-aryl migration to the synthesis of substituted indoles.
Tao Pei et al.
Angewandte Chemie (International ed. in English), 47(22), 4231-4233 (2008-04-30)
Anil K Nigam et al.
Journal of hazardous materials, 184(1-3), 506-514 (2010-09-17)
Pyrolysis-GC/MS system with on-line micro-furnace was used to make rapid evaluation of ω-chloroacetophenone (CN) decomposition under inert thermal atmospheres. The volatile products evolved during pyrolysis were analyzed by thermal gravimetric analysis (TGA) and Py-GC/MS to obtain specific thermogram and pyrogram.
Wladimir Solodenko et al.
Molecular diversity, 9(4), 333-339 (2005-11-29)
The preparation of a new palladium(II) complex with a 2-pyridinealdoxime ligand and its use as a Pd(0) precatalyst in the cross-coupling Suzuki-Miyaura reaction is described. Several concepts for the immobilization of this catalytic system are presented and compared in order
Lenilson C Rocha et al.
Biotechnology letters, 31(10), 1559-1563 (2009-06-06)
The asymmetric reduction of 2-chloro-1-phenylethanone (1) by seven strains of marine fungi was evaluated and afforded (S)-(-)-2-chloro-1-phenylethanol with, in the best case, an enantiomeric excess of 50% and an isolated yield of 60%. The ability of marine fungi to catalyse
Qing Xie et al.
Biotechnology progress, 22(5), 1301-1304 (2006-10-07)
The asymmetric reduction of o-chloroacetophenone 1 with Candida pseudotropicalis 104 produced the corresponding (S)-1-(2-chloro-phenyl)-ethanol 2 with the enantiomeric excess (ee >99%) without addition of any cosolvent. The cell could tolerate high ketone 1 concentration of 233.8 mmol/L (i.e., 36 g/L)

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