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Merck
CN

C1761

分支酸 来源于产气肠杆菌

≥80%

别名:

反式-3-([1-羧基乙烯基]氧)-4-羟基-1,5-环己二烯-1-羧酸

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关于此项目

经验公式(希尔记法):
C10H10O6
化学文摘社编号:
分子量:
226.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
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产品名称

分支酸 来源于产气肠杆菌, ≥80%

InChI

1S/C10H10O6/c1-5(9(12)13)16-8-4-6(10(14)15)2-3-7(8)11/h2-4,7-8,11H,1H2,(H,12,13)(H,14,15)/t7-,8-/m1/s1

SMILES string

O[C@@H]1C=CC(=C[C@H]1OC(=C)C(O)=O)C(O)=O

InChI key

WTFXTQVDAKGDEY-HTQZYQBOSA-N

assay

≥80%

form

powder

shipped in

dry ice

storage temp.

−20°C

Quality Level

Application

分支酸是一种代谢物,通常用于研究分支酸-预苯酯重排和合成分支酸衍生物。
通过莽草酸途径生物合成芳香氨基酸的中间体。

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Stabilization of the transition state of the chorismate-prephenate rearrangement: An ab initio study of enzyme and antibody catalysis.
Wiest, Olaf and Houk, KN
Journal of the American Chemical Society, 117(47), 11628-11639 (1995)
Diversity-oriented production of metabolites derived from chorismate and their use in organic synthesis.
Johannes Bongaerts et al.
Angewandte Chemie (International ed. in English), 50(34), 7781-7786 (2011-07-09)
Richard J Payne et al.
Organic & biomolecular chemistry, 8(15), 3534-3542 (2010-06-10)
Several 2-amino-4-carboxypyridine, 4- and 5-carboxypyridone-based compounds were prepared and tested against three members of the chorismate-utilising enzyme family, anthranilate synthase, isochorismate synthase and salicylate synthase. Most compounds exhibited low micromolar inhibition of these three enzymes. The most potent inhibitor was
Of two make one: the biosynthesis of phenazines.
Matthias Mentel et al.
Chembiochem : a European journal of chemical biology, 10(14), 2295-2304 (2009-08-07)
Sergio Martí et al.
Journal of the American Chemical Society, 131(44), 16156-16161 (2009-10-20)
The isochorismate pyruvate lyase (IPL) from Pseudomonas aeruginosa, designated as PchB, catalyzes the transformation of isochorismate into pyruvate and salicylate, but it also catalyzes the rearrangement of chorismate into prephenate, suggesting that both reactions may proceed by a pericyclic mechanism.

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