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Merck
CN

C1761

Sigma-Aldrich

分支酸 来源于产气肠杆菌

≥80%

别名:

反式-3-([1-羧基乙烯基]氧)-4-羟基-1,5-环己二烯-1-羧酸

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About This Item

经验公式(希尔记法):
C10H10O6
CAS号:
分子量:
226.18
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

≥80%

表单

powder

运输

dry ice

储存温度

−20°C

SMILES字符串

O[C@@H]1C=CC(=C[C@H]1OC(=C)C(O)=O)C(O)=O

InChI

1S/C10H10O6/c1-5(9(12)13)16-8-4-6(10(14)15)2-3-7(8)11/h2-4,7-8,11H,1H2,(H,12,13)(H,14,15)/t7-,8-/m1/s1

InChI key

WTFXTQVDAKGDEY-HTQZYQBOSA-N

应用

分支酸是一种代谢物,通常用于研究分支酸-预苯酯重排和合成分支酸衍生物。
通过莽草酸途径生物合成芳香氨基酸的中间体。

象形图

Health hazardExclamation mark

警示用语:

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Gamma Chi et al.
Biochemistry, 51(24), 4868-4879 (2012-05-23)
MbtI is the salicylate synthase that catalyzes the first committed step in the synthesis of the iron chelating compound mycobactin in Mycobacterium tuberculosis. We previously developed a series of aromatic inhibitors against MbtI based on the reaction intermediate for this
The mechanism of rearrangement of chorismic acid and related compounds.
Gajewski, Joseph J et al.
Journal of the American Chemical Society, 109(4), 1170-1186 (1987)
Expanding the genetic code.
Wang, Lei and Schultz, Peter G
Angewandte Chemie (International Edition in English), 44(1), 34-66 (2005)
Nivedita Nagachar et al.
FEMS microbiology letters, 308(2), 159-165 (2010-05-22)
Mycobacterium smegmatis acquires extracellular iron using exochelin, mycobactin and carboxymycobactin. The latter two siderophores are synthesized from salicylic acid, which, in turn, is derived from chorismic acid in the shikimic acid pathway. To understand the conversion mechanism of chorismic acid
Alexandra Choutko et al.
Protein science : a publication of the Protein Society, 21(11), 1672-1681 (2012-08-18)
The protein chorismate mutase MtCM from Mycobacterium tuberculosis catalyzes one of the few pericyclic reactions known in biology: the transformation of chorismate to prephenate. Chorismate mutases have been widely studied experimentally and computationally to elucidate the transition state of the

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