生物来源
synthetic (organic)
质量水平
检测方案
98%
形式
crystalline powder
powder or crystals
mp
156 °C (dec.) (lit.)
溶解性
water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
储存温度
2-8°C
SMILES字符串
Cl.NOCC(O)=O.NOCC(O)=O
InChI
1S/2C2H5NO3.ClH/c2*3-6-1-2(4)5;/h2*1,3H2,(H,4,5);1H
InChI key
KBXIJIPYZKPDRU-UHFFFAOYSA-N
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应用
半盐酸盐 O-(羧甲基)羟胺可作为反应物通过与醛和酮缩合合成肟。它还可作为(吡哆醛 5’-磷酸) PLP-依赖性 β-裂解酶的有效抑制剂。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Characterization of a 5'-aldehyde terminus resulting from the oxidative attack at C5 `of a 2-deoxyribose on DNA
Angeloff A, et al.
Chemical Research in Toxicology, 14, 1413-1420 (2001)
Tissue distribution of cytosolic beta-elimination reactions of selenocysteine Se-conjugates in rat and human
Rooseboom M, et al.
Chemico-Biological Interactions, 140, 243-264 (2002)
Tetrahedron Letters, 34, 4347-4347 (1993)
Ches'Nique M Phillips et al.
Cancer research, 77(21), 5741-5754 (2017-09-20)
The trans-sulfuration enzyme cystathionine-β-synthase (CBS) and its product hydrogen sulfide (H2S) are aberrantly upregulated in colorectal cancers, where they contribute to tumor growth and progression by both autocrine and paracrine mechanisms. However, it is unknown whether the CBS/H2S axis plays
Lucía Trilla-Fuertes et al.
BMC cancer, 20(1), 307-307 (2020-04-16)
Metabolomics has a great potential in the development of new biomarkers in cancer and it has experiment recent technical advances. In this study, metabolomics and gene expression data from 67 localized (stage I to IIIB) breast cancer tumor samples were
商品
本文介绍了增殖活性细胞为何需要碳源和氮源合成大分子。尽管大部分肿瘤细胞利用有氧糖酵解途径并分流线粒体氧化磷酸化代谢物，但许多肿瘤细胞表现出线粒体活性增加。
Sigma article discusses tumor cell metabolic pathways, focusing on aerobic glycolysis and mitochondrial activity.
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