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Merck
CN

C117307

Sigma-Aldrich

溴代环丙烷

99%

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别名:
环丙基溴
经验公式(希尔记法):
C3H5Br
CAS号:
分子量:
120.98
Beilstein:
1900287
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

99%

形式

liquid

折射率

n20/D 1.458 (lit.)

bp

69 °C (lit.)

密度

1.51 g/mL at 25 °C (lit.)

储存温度

2-8°C

SMILES字符串

BrC1CC1

InChI

1S/C3H5Br/c4-3-1-2-3/h3H,1-2H2

InChI key

LKXYJYDRLBPHRS-UHFFFAOYSA-N

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一般描述

溴环丙烷是有机合成的关键中间体,也是药物开发中构建多种化学结构的基础材料。

象形图

Flame

警示用语:

Danger

危险声明

危险分类

Flam. Liq. 2

WGK

WGK 3

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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Mechanism-Driven Elaboration of an Enantioselective Bromocyclopropanation Reaction of Allylic Alcohols
S Taillemaud, et al.
Angewandte Chemie (International Edition in English), 127, 14314-14318 (2015)
John R Hornick et al.
Journal of experimental & clinical cancer research : CR, 31, 41-41 (2012-05-04)
Sigma-2 receptor ligands have been studied for treatment of pancreatic cancer because they are preferentially internalized by proliferating cells and induce apoptosis. This mechanism of apoptosis is poorly understood, with varying reports of caspase-3 dependence. We evaluated multiple sigma-2 receptor
Carmen Abate et al.
ChemMedChem, 6(1), 73-80 (2010-11-12)
Many new chemotherapeutic agents are under preclinical investigation and, despite efforts to more selectively target cancer cells, limitations such as toxicity and inherent resistance are often encountered. Therefore, alternative strategies are needed to treat cancer and overcome such limitations. We
Carmen Abate et al.
Journal of medicinal chemistry, 57(8), 3314-3323 (2014-04-05)
Despite the promising potentials of σ2 receptors in cancer therapy and diagnosis, there are still ambiguities related to the nature and physiological role of the σ2 protein. With the aim of providing potent and reliable tools to be used in
Maria Laura Pati et al.
Pharmacological research, 117, 67-74 (2016-12-23)
A controversial relationship between sigma-2 and progesterone receptor membrane component 1 (PGRMC1) proteins, both representing promising targets for the therapy and diagnosis of tumors, exists since 2011, when the sigma-2 receptor was reported to be identical to PGRMC1. Because a

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