推荐产品
质量水平
方案
99%
表单
powder
沸点
297-298 °C (lit.)
mp
65-67 °C (lit.)
SMILES字符串
OC(c1ccccc1)c2ccccc2
InChI
1S/C13H12O/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,13-14H
InChI key
QILSFLSDHQAZET-UHFFFAOYSA-N
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应用
二苯基甲醇用于卡宾催化的α，α-二取代羧酸酯的动态动力学拆分。也可用于游离碱和 Ni (II) 卟啉配合物的手性拆分。
储存分类代码
11 - Combustible Solids
WGK
WGK 2
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Carbene-Catalyzed Dynamic Kinetic Resolution of Carboxylic Esters.
Chen X, et al.
Journal of the American Chemical Society, 138(23), 7212-7215 (2016)
Helimeric porphyrinoids: stereostructure and chiral resolution of meso-tetraarylmorpholinochlorins.
Bru?ckner C, et al.
Journal of the American Chemical Society, 133(22), 8740-8752 (2011)
Alkylation of alcohols for gas chromatographic analysis by a phase transfer catalysis technique. Evaluation of benzhydrol benzylation in a one-phase system.
H Brink et al.
Acta pharmaceutica Suecica, 16(4), 247-262 (1979-01-01)
Masanori Ichikawa et al.
Bioorganic & medicinal chemistry, 20(9), 3072-3093 (2012-04-03)
In the present article, we have reported the design, synthesis, and identification of highly potent benzhydrol derivatives as squalene synthase inhibitors (compound 1). Unfortunately, the in vivo efficacies of the compounds were not enough for acquiring the clinical candidate. We
Xiao-Dong Ma et al.
Bioorganic & medicinal chemistry, 19(16), 4704-4709 (2011-07-27)
A series of (±)-benzhydrol derivatives featuring the essential sulfonamide group at the para position on the C-ring were synthesized and evaluated for the potential anti-HIV activity in C8166 cells. Most of these analogues demonstrated low concentration inhibitory activity with EC(50)
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