Aldrich^® 微光化学反应器，蓝色 LED 灯

Photocatalysis in organic synthesis has grown with innovative methods using visible light, contributing to new research.

This review provides a summary of recent approaches in developing green methods for visible-light-mediated reactions that operate under mild conditions and avoid the need for toxic transition-metal catalysts or harsh reaction conditions.

This article details the latest progress in synthesizing alkylsulfonyl fluorides through different approaches that utilize photoredox catalysis, electrocatalysis, transition-metal catalysis, and organocatalysis. The alkylsulfonyl fluorides thus prepared could be utilized further in sulfur(VI) fluoride exchange (SuFEx) click reactions.

One major theme of research in the Yoon lab is the development of unique chemical transformations enabled by visible light photochemistry. A variety of transition metal photocatalysts responsive to visible light are known, and the Yoon lab has shown that their well understood photochemistry can be coupled to cycloadditions, arene oxidations, amine functionalizations, and thiol-ene reactions, among others.