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质量水平
方案
≥95%
表单
powder
反应适用性
reagent type: catalyst
reagent type: ligand
reaction type: C-H Activation
SMILES字符串
CC1=C2C(OC(C)CC2)=NC3=C1C(C)=CC(C)=C3
InChI
1S/C16H19NO/c1-9-7-10(2)15-12(4)13-6-5-11(3)18-16(13)17-14(15)8-9/h7-8,11H,5-6H2,1-4H3
InChI key
LOKRNFHHPZEJLL-UHFFFAOYSA-N
一般描述
Yu Fluorination Ligand is widely employed for the chemoselective functionalization of sp2- and sp3 C-H bonds.
应用
The Yu Fluorination Ligand in tandem with Selectfluor(R) (Aldrich 439479) under palladium catalysis can promote direct fluorination of C(sp3)-H bonds stereoselectively. Yu and coworkers have displayed this on amino acid derivatives with directing group assistance from the Yu-Wasa Auxiliary (Aldrich 791806).
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
相关内容
Yu program focuses on efficient C–H bond activation for drug synthesis, using simple starting materials.
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