方案
≥98%
表单
crystals
mp
111-113 °C (lit.)
荧光
λex 330 nm; λem 420 nm(lit.)
SMILES字符串
NC(=O)c1ccccc1N
InChI
1S/C7H8N2O/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H2,9,10)
InChI key
PXBFMLJZNCDSMP-UHFFFAOYSA-N
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应用
用于非选择性高效荧光标记聚糖。荧光标记灵敏度略低于邻氨基苯甲酸 (2-AA)。
荧光标记含有游离还原末端的聚糖。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
>365.0 °F
闪点(°C)
> 185 °C
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Jia Jia et al.
Organic & biomolecular chemistry, 10(31), 6279-6286 (2012-06-23)
Three fluorescent probes CdABA', CdABA and ZnABA', which are structural isomers of ZnABA, have been designed with N,N-bis(2-pyridylmethyl) ethylenediamine (BPEA) as chelator and 2-aminobenzamide as fluorophore. These probes can be divided into two groups: CdABA, CdABA' for Cd(2+) and ZnABA
Udayanath Aich et al.
The FEBS journal, 278(10), 1699-1712 (2011-03-18)
Agglutination of red blood cells (RBCs), including chicken RBCs (cRBCs), has been used extensively to estimate viral titer, to screen glycan-receptor binding preference, and to assess the protective response of vaccines. Although this assay enjoys widespread use, some virus strains
Bing Xia et al.
The Journal of organic chemistry, 78(5), 1994-2004 (2012-12-29)
As electrostatic equivalents of magnets, organic electrets offer unparalleled properties for impacting energy conversion and electronic applications. While biological systems have evolved to efficiently utilize protein α-helices as molecular electrets, the synthetic counterparts of these conjugates still remain largely unexplored.
Ada Triguero et al.
Analytical biochemistry, 400(2), 173-183 (2010-01-30)
Plants synthesize N-glycans containing the antigenic sugars alpha(1,3)-fucose and beta(1,2)-xylose. Therefore it is important to monitor these N-glycans in monoclonal antibodies produced in plants (plantibodies). We evaluated several techniques to characterize the N-glycosylation of a plantibody produced in tobacco plants
Joomi Ahn et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(3-4), 403-408 (2009-12-29)
Separation by hydrophilic interaction chromatography (HILIC) with fluorescence detection utilizing a sub-2 microm glycan column for the separation of 2-aminobenzamide (2-AB) labeled N-linked glycans is described. The HILIC column packed with a 1.7 microm amide sorbent improves the peak capacity
商品
Glycans play a key role in protein structure and disease; representation on cell surfaces is the glycome.
蛋白质的结构修饰对于活细胞是必不可少的。发生调节异常时,它们往往是会引发疾病。聚糖是生物系统中许多结构变异的原因,它们在细胞表面的表现通常被称为“糖”。
实验方案
Explore mass spectrometry analysis of glycans for glycomic & glycoproteomic neutral & acidic glycan analysis. See a general mass spec glycan analysis procedure.
该聚糖质谱分析方案,被称之为干液滴法,基于原始的MALDI实验并依然是MS领域中最常用的方法。
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