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质量水平
方案
97%
表单
powder
mp
115-117 °C (lit.)
SMILES字符串
Nc1ccc2ccc3cccc4ccc1c2c34
InChI
1S/C16H11N/c17-14-9-7-12-5-4-10-2-1-3-11-6-8-13(14)16(12)15(10)11/h1-9H,17H2
InChI key
YZVWKHVRBDQPMQ-UHFFFAOYSA-N
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应用
- 用于超临界液相色谱扩展用途、基于线性溶剂化能量关系模型（ linear solvation energy relationship model）的芳香族固定相的合成和评估：探讨了利用1-氨基芘开发先进色谱固定相，增进了药物和环境分析的效率和应用范围（Ge et al., 2024）。
- 作为化学选择性氢化光催化平台的二维卟啉金属-有机框架复合材料：重点介绍了将1-氨基芘引入金属-有机框架，为用于有机合成的高效光催化系统的创建提供了一条新途径，对学术研究和工业化学制造都有重大意义（Dong et al., 2023）。
- 利用并设计用于催化卡宾N-H插入和羟基喹喔啉形成的神经珠蛋白。：讨论了1-氨基芘在促进工程蛋白（engineered proteins）中酶促反应的作用，为药物研究中的新型合成途径铺平了道路 （Sun et al., 2023）。
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
O Wongwattanasathien et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48(4), 1045-1051 (2010-01-27)
The mutagenicity of dichloromethane, methanol and water extracts of Antigonon leptopus Hook. & Arn., Curcuma sessilis Gage, Hibiscus rosa-sinensis Linn., Ixora coccinea Linn., Millingtonia hortensis Linn., Nelumbo nucifera Gaertn., Plumeria obtusa Linn., Punica granatum Linn., Rhinacanthus nasutus ((Linn.) Kurz.) and
A Ferancová et al.
Bioelectrochemistry (Amsterdam, Netherlands), 67(2), 191-197 (2005-08-27)
The aim of this work was voltammetric determination of 1-aminopyrene and 1-hydroxypyrene using carbon paste electrodes modified with cyclodextrin derivatives and double stranded deoxyribonucleic acid (dsDNA). The detection schemes based on a preconcentration and differential pulse voltammetric (DPV) determination at
R Shapiro et al.
Chemical research in toxicology, 11(4), 335-341 (1998-05-05)
While the one-ring amine aniline (AN) has only slight genetic activity, the polycyclic aromatic amines 2-aminofluorene (AF) and 1-aminopyrene (AP) are significant mutagens and carcinogens. Moreover, the bulkier AP is more mutagenic per adduct than AF in the tetracycline-resistance gene
P D Josephy et al.
Mutation research, 429(2), 199-208 (1999-10-20)
The mutagenic actions of many chemicals depend on the activities of bacterial "mutagenesis proteins", which allow replicative bypass of DNA lesions. Genes encoding these proteins occur on bacterial chromosomes and plasmids, often in the form of an operon (such as
B Mao et al.
Biochemistry, 35(39), 12659-12670 (1996-10-01)
Combined NMR-molecular mechanics computational studies were undertaken on the C8-deoxyguanosine adduct formed by the carcinogen 1-nitropyrene embedded in the d(C5-[AP]G6-C7).d(G16-C17-G18) sequence context in a 11-mer duplex, with dC opposite the modified deoxyguanosine. The exchangeable and nonexchangeable protons of the aminopyrene
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