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Merck
CN

A76427

3-氨基丙腈 富马酸盐

≥99%

别名:

β-丙炔腈

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关于此项目

线性分子式:
NH2CH2CH2CN · ½ (HO2CCH=CHCO2H)
化学文摘社编号:
分子量:
128.13
EC Number:
218-208-7
UNSPSC Code:
12352103
Beilstein/REAXYS Number:
3573532
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InChI key

NYMXYZMHOZAPHQ-SEPHDYHBSA-N

InChI

1S/C4H4O4.2C3H6N2/c5-3(6)1-2-4(7)8;2*4-2-1-3-5/h1-2H,(H,5,6)(H,7,8);2*1-2,4H2/b2-1+;;

SMILES string

NCCC#N.NCCC#N.OC(=O)\C=C\C(O)=O

assay

≥99%

mp

177 °C (dec.) (lit.)

Biochem/physiol Actions

在哺乳动物中,3-氨基丙腈的代谢会导致氰离子的释放。代谢活性集中在肝微粒体部分,并被认为是通过自由基途径进行的。

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

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分析证书(COA)

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G Granström et al.
Scandinavian journal of plastic and reconstructive surgery and hand surgery, 26(1), 13-20 (1992-01-01)
Cleft palate was induced in 420 embryos of Sprague-Dawley rats with a single oral dose of 600 mg/kg beta-aminoproprionitrile (BAPN) on embryonal day 15, 7 hours. The cleft palate was accompanied by a pathological differentiation pattern of various isoenzymes in
D L Hoffman et al.
Experimental and molecular pathology, 39(2), 154-162 (1983-10-01)
beta-Aminopropionitrile as free base (BAPN) was applied onto the incised or intact skin of rats at the dose of 5, 20, 100, and 200 microliters for 9 days, twice daily. Breaking strength of the skin wound or intact skin was
Hirotaka Nagashima et al.
Journal of vascular surgery, 36(4), 818-823 (2002-10-09)
Cystic medial degeneration (CMD) is a histologic abnormality that is common in aortic diseases such as aortic dilation, aneurysm, or dissection. Although little is known about the mechanism underlying CMD, we have previously demonstrated that angiotensin II signaling via angiotensin
Possibilities for the therapeutic control of fibrosis.
C I Levene
The British journal of dermatology, 112(3), 363-371 (1985-03-01)
S Gunasekaran et al.
Surgical neurology, 28(3), 201-207 (1987-09-01)
The purpose of this study is to evaluate possible toxic effects of beta-aminopropionitrile fumarate (beta APN), a lathyrogenic agent that inhibits fibrosis. This drug has been considered for use as an adjunct to surgical repair after topical application upon peripheral

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