InChI key
NYMXYZMHOZAPHQ-SEPHDYHBSA-N
InChI
1S/C4H4O4.2C3H6N2/c5-3(6)1-2-4(7)8;2*4-2-1-3-5/h1-2H,(H,5,6)(H,7,8);2*1-2,4H2/b2-1+;;
SMILES string
NCCC#N.NCCC#N.OC(=O)\C=C\C(O)=O
assay
≥99%
mp
177 °C (dec.) (lit.)
Biochem/physiol Actions
在哺乳动物中,3-氨基丙腈的代谢会导致氰离子的释放。代谢活性集中在肝微粒体部分,并被认为是通过自由基途径进行的。
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
G Granström et al.
Scandinavian journal of plastic and reconstructive surgery and hand surgery, 26(1), 13-20 (1992-01-01)
Cleft palate was induced in 420 embryos of Sprague-Dawley rats with a single oral dose of 600 mg/kg beta-aminoproprionitrile (BAPN) on embryonal day 15, 7 hours. The cleft palate was accompanied by a pathological differentiation pattern of various isoenzymes in
D L Hoffman et al.
Experimental and molecular pathology, 39(2), 154-162 (1983-10-01)
beta-Aminopropionitrile as free base (BAPN) was applied onto the incised or intact skin of rats at the dose of 5, 20, 100, and 200 microliters for 9 days, twice daily. Breaking strength of the skin wound or intact skin was
Hirotaka Nagashima et al.
Journal of vascular surgery, 36(4), 818-823 (2002-10-09)
Cystic medial degeneration (CMD) is a histologic abnormality that is common in aortic diseases such as aortic dilation, aneurysm, or dissection. Although little is known about the mechanism underlying CMD, we have previously demonstrated that angiotensin II signaling via angiotensin
Possibilities for the therapeutic control of fibrosis.
C I Levene
The British journal of dermatology, 112(3), 363-371 (1985-03-01)
S Gunasekaran et al.
Surgical neurology, 28(3), 201-207 (1987-09-01)
The purpose of this study is to evaluate possible toxic effects of beta-aminopropionitrile fumarate (beta APN), a lathyrogenic agent that inhibits fibrosis. This drug has been considered for use as an adjunct to surgical repair after topical application upon peripheral
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