质量水平
检测方案
≥98%
形式
granular
powder or crystals
mp
185-189 °C (lit.)
溶解性
water: slightly soluble
SMILES字符串
Nc1ccc(O)cc1
InChI
1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2
InChI key
PLIKAWJENQZMHA-UHFFFAOYSA-N
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一般描述
4-氨基苯酚（4-羟基苯胺）是一种有机合成砌块。采用单壁碳纳米管（SWNT）-氟化钠薄膜涂层玻碳电极，对水样进行定量分析，定量结果可达到8×10-10mol-1 的检出限。它是对乙酰氨基酚的药物制剂中的主要污染物。使用安培检测高效液相色谱（HPLC）法对各种镇痛制剂进行测定已有报道。据报道，在无金属和 N-掺杂石墨烯（NG）催化条件下，它可通过还原4-硝基苯酚（Nip）而形成。
应用
4-氨基苯酚适用于合成2,2-双（4-氨基苯氧基）苄腈[4-APBN]，这是制备一系列聚酰胺和聚（酰胺-酰亚胺）所需的单体。 它可以用作衍生化试剂，通过纸喷雾电离质谱法改善脂肪族和芳香族醛的电离。
警示用语：
Warning
危险分类
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2 - Skin Sens. 1 - STOT RE 2
靶器官
Kidney
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
危险化学品
Saxena A, et al.
Eur. Polymer J., 39(2), 401-405 (2003)
Metal-free catalytic reduction of 4-nitrophenol to 4-aminophenol by N-doped graphene.
Kong XK, et al.
Energy & Environmental Science, 6(11), 3260-3266 (2013)
E Wyszecka-Kaszuba et al.
Journal of pharmaceutical and biomedical analysis, 32(4-5), 1081-1086 (2003-08-06)
A method for the determination of 4-aminophenol, the main impurity of paracetamol, by high-performance liquid chromatographic (HPLC) method with amperometric detection has been developed. The analysis was performed in an isocratic mode on a reversed phase Luna column 5 microm
Wensheng Huang et al.
Talanta, 61(3), 411-416 (2008-10-31)
A single-wall carbon nanotubes (SWNT)-Nafion film coated glassy carbon electrode (GCE) was described for the determination of 4-aminophenol. In pH 3.0 sodium citrate-HCl buffer, the oxidation peak current of 4-aminophenol increases greatly at the SWNT-Nafion film coated GCE in contrast
Y Xu et al.
Clinical chemistry, 36(11), 1941-1944 (1990-11-01)
A sandwich-type heterogeneous enzyme immunoassay with flow-injection analysis for alpha-fetoprotein (AFP) in human serum has been developed. 4-Aminophenol, the product of enzymatic reaction, is detected amperometrically. The interassay CV for this electrochemical enzyme immunoassay was less than 8.2%, with a
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