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关于此项目
经验公式(希尔记法):
C6H7N3O
化学文摘社编号:
分子量:
137.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
206-349-7
Beilstein/REAXYS Number:
116042
MDL number:
产品名称
6-氨基烟酰胺, 99%
InChI key
ZLWYEPMDOUQDBW-UHFFFAOYSA-N
InChI
1S/C6H7N3O/c7-5-2-1-4(3-9-5)6(8)10/h1-3H,(H2,7,9)(H2,8,10)
SMILES string
NC(=O)c1ccc(N)nc1
assay
99%
form
powder
mp
245-248 °C (lit.)
Quality Level
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Application
6-氨基烟酰胺可作为以下应用的反应物:
- 合成6-取代的咪唑并[1,2-a吡啶,此产物有可能作为化学治疗药物。
- 脱水 N-单苄基化过程。
General description
6-氨基烟酰胺是氨基吡啶,为特异性戊糖抑制剂,抑制 NADP产生。
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
A borrowing hydrogen methodology: palladium-catalyzed dehydrative N-benzylation of 2-aminopyridines in water.
Hikawa H, et al.
Green Chemistry, 20(13), 3044-3049 (2018)
L Poulain et al.
Leukemia, 31(11), 2326-2335 (2017-03-11)
Alterations in metabolic activities are cancer hallmarks that offer a wide range of new therapeutic opportunities. Here we decipher the interplay between mTORC1 activity and glucose metabolism in acute myeloid leukemia (AML). We show that mTORC1 signaling that is constantly
6-Substituted imidazo [1, 2-a] pyridines: Synthesis and biological activity against colon cancer cell lines HT-29 and Caco-2.
Dahan-Farkas N, et al.
European Journal of Medicinal Chemistry, 46(9), 4573-4583 (2011)
Electrocatalytic synthesis of 6-aminonicotinic acid at silver cathodes under mild conditions.
Gennaro A, et al.
Electrochemical Communications, 6(7), 627-631 (2004)
Jorge Domínguez-Andrés et al.
PLoS pathogens, 13(9), e1006632-e1006632 (2017-09-19)
Monocytes are innate immune cells that play a pivotal role in antifungal immunity, but little is known regarding the cellular metabolic events that regulate their function during infection. Using complementary transcriptomic and immunological studies in human primary monocytes, we show
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