A47052
6-氨基屈
95%
别名:
7-胺基去乙酰氧基头胞烷酸
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关于此项目
经验公式（希尔记法）:
C18H13N
化学文摘社编号:
分子量:
243.30
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
220-149-7
MDL number:
Assay:
95%
Form:
solid
InChI key
KIVUHCNVDWYUNP-UHFFFAOYSA-N
InChI
1S/C18H13N/c19-18-11-17-13-6-2-1-5-12(13)9-10-15(17)14-7-3-4-8-16(14)18/h1-11H,19H2
SMILES string
Nc1cc2c3ccccc3ccc2c4ccccc14
assay
95%
form
solid
mp
209-211 °C (lit.)
Quality Level
Application
诱发小鼠肿瘤。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Carcinogenicity of 6-aminochrysene in mice.
G Lambelin et al.
European journal of cancer, 11(5), 327-334 (1975-05-01)
R A Lubet et al.
Mutation research, 212(2), 275-284 (1989-06-01)
6-Aminochrysene and 2-aminoanthracene were activated to metabolites which were mutagenic to Salmonella typhimurium TA98 by hepatocytes or hepatic 9000 X g supernatants (S9s) from control or xenobiotic-treated rats. Hepatocytes from Aroclor-1254-treated rats were more efficient than hepatocytes from untreated rats
S Lahmy et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 35(2), 197-201 (1987-02-01)
The purpose of this study was to determine if dibenzo(c,h)acridine could be used as a probe for the N-heterocyclic aromatic compound detoxification system. The determination was achieved by cell population studies (histograms) using microspectrofluorimetry on single living cells. The results
H Yamazaki et al.
Carcinogenesis, 14(7), 1271-1278 (1993-07-01)
We reported previously that the potent mutagen 6-aminochrysene is catalyzed principally by rat liver microsomal P4501A and P4502B enzymes to reactive metabolites that induce umu gene expression in O-acetyltransferase-over-expressing strain Salmonella typhimurium NM2009; the proposal was made that there are
K B Delclos et al.
Cancer research, 47(23), 6272-6277 (1987-12-01)
6-Nitrochrysene (NC) and 6-aminochrysene (AC) have been shown to be potent lung and liver carcinogens when administered in multiple i.p. doses to preweanling mice. 1,6-Dinitropyrene has been shown to be a strong hepatocarcinogen but a weak lung carcinogen in this
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