A10000
丙酮氰醇
99%
别名:
α-羟基异丁腈, 2-羟基异丁腈
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关于此项目
线性分子式:
(CH3)2C(OH)CN
化学文摘社编号:
分子量:
85.10
UNSPSC Code:
12352100
NACRES:
NA.02
PubChem Substance ID:
EC Number:
200-909-4
Beilstein/REAXYS Number:
605391
MDL number:
Assay:
99%
Form:
liquid
InChI
1S/C4H7NO/c1-4(2,6)3-5/h6H,1-2H3
InChI key
MWFMGBPGAXYFAR-UHFFFAOYSA-N
SMILES string
CC(C)(O)C#N
vapor pressure
0.3 psi ( 20 °C)
assay
99%
form
liquid
contains
H3PO4 as stabilizer (Europe), sulfuric acid as stabilizer (US)
expl. lim.
11 %
refractive index
n20/D 1.399 (lit.)
bp
82 °C/23 mmHg (lit.)
mp
−19 °C (lit.)
density
0.932 g/mL at 25 °C (lit.)
Quality Level
General description
丙酮氰醇可用作Mitsunobu 反应中的氢氰酸源。也是甲基丙烯酰胺合成的中间体。
Application
丙酮氰醇可用作以下反应的氰化物来源：
- 芳基卤化物、 醛类 和酒精的氰化反应。
- 立体特异性环氧化物开环反应。
- α-酰胺基砜的Strecker 反应，以合成 α-氨基腈。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
167.0 °F - closed cup
flash_point_c
75 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
监管及禁止进口产品
此项目有
H Lauble et al.
Protein science : a publication of the Protein Society, 10(5), 1015-1022 (2001-04-24)
The structure and function of hydroxynitrile lyase from Manihot esculenta (MeHNL) have been analyzed by X-ray crystallography and site-directed mutagenesis. The crystal structure of the MeHNL-S80A mutant enzyme has been refined to an R-factor of 18.0% against diffraction data to
Regiospecific opening of 1, 2-expoxides with acetone cyanohydrin under mildly basic conditions.
Mitchell D and Koenig TM
Tetrahedron Letters, 33(23), 3281-3284 (1992)
Rondon Tosta Ramalho et al.
Acta cirurgica brasileira, 25(1), 111-116 (2010-02-04)
To evaluate the antitumor effect of acetone cyanohydrin in Ehrlich ascites tumor cells in vitro. The Ehrlich ascites tumor cells and lymphocytes were incubated with different concentrations of acetone cyanohydrin (0, 0.5, 1.0, 2.0, 10.0, 20.0 and 30.0 microg x
Z I Zholdakova et al.
Gigiena i sanitariia, (8)(8), 16-18 (1994-09-01)
The study of acetone cyanohydrin (ACH) showed that it is an unstable substance. Its stability in water depends on pH of water and less so on its initial concentration; water temperature and biota are insignificant. Acetone and cyanid-ion, forming from
[Method of determining the level of rodanides in biological matter].
O V Shekhter et al.
Gigiena i sanitariia, (2)(2), 54-55 (1994-02-01)
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