NanoFabTx^™ photoactivatable lipid mix

The NanoFabTx^™ photoactivatable AzoPC lipid mix can be used to:

• Enable the synthesis of photoactivatable liposomes for targeted drug delivery
• Allow controlled release of payload upon photoactivation
• Research and development in the field of targeted cancer therapy and drug delivery technologies

• A ready-to-use lipid blend for the synthesis of photoactivatable liposomes.
• Step-by-step protocols (microfluidics) developed and tested by our formulation scientists
• Flexible synthesis tool to create uniform and reproducible liposomes

Comprehensive protocols for liposome synthesis are included:

• A microfluidics protocol using commercial platforms or syringe pumps

The microfluidics protocol included with this product uses the NanoFabTx^™ device kit (911593). These kits come with the microfluidics chips, fittings, and tubing required to get started with microfluidics-based synthesis (compatible microfluidics system or syringe pump required).

About the material:

NanoFabTx^™ AzoPC Lipid Mix is a curated lipid mixture designed for the synthesis of photoactivatable liposomes. This ready-to-use lipid mix contains carefully selected lipids and comes with detailed step-by-step instructions for the synthesis process.

The photoactivatable lipid AzoPC exhibits cytotoxicity upon exposure to UV-A light in human cancer cell lines, leading to the release of its payload upon photoactivation. Notably, the photoactivatable liposomes themselves are non-cytotoxic in the absence of light.

For further details and a comprehensive step-by-step protocol, please refer to the "More Documents" section on this page.

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC