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Merck
CN

939765

Sigma-Aldrich

Tri(ethylene glycol) (N-hydroxyethoxy)ethyl methacrylamide

new

contains 200 ppm MEHQ

别名:

Hydrogels

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About This Item

经验公式(希尔记法):
C26H48N2O10
分子量:
548.67
UNSPSC代码:
12162008

表单

liquid (Viscous Liquid or Paste)

质量水平

包含

200 ppm MEHQ

颜色

colorless to yellow

储存温度

−20°C

SMILES字符串

O=C(C(C)=C)NCCOCCOC(C)OCCOCCOCCOC(C)OCCOCCNC(C(C)=C)=O

InChI

1S/C26H48N2O10/c1-21(2)25(29)27-7-9-31-13-17-35-23(5)37-19-15-33-11-12-34-16-20-38-24(6)36-18-14-32-10-8-28-26(30)22(3)4/h23-24H,1,3,7-20H2,2,4-6H3,(H,27,29)(H,28,30)

InChI key

CQIHNSAQHHTPKN-UHFFFAOYSA-N

一般描述

Tri(ethylene glycol) (N-hydroxyethoxy)ethyl methacrylamide is a pH sensitive crosslinker and monomer containing an acetal group. The acetal group of the monomer is degraded upon acidic conditions and yields neutral degradation product. This monomer and crosslinker can be used in the synthesis of polyacetals which can be used in a variety of applications due to their instrinsically biodegradable properties. Additionally, they can exhibit (lower critical solution temperature) LCST behavior where they lose solubility upon heating.

应用

  • Targeted drug delivery application
  • Controlled or sustained drug delivery
  • As a pH clevable crosslinker
  • Polyacetal polymer synthesis
  • Stimuli responsive hydrogels

特点和优势

  • Unique degradation mechanism -Degrades in acidic condition and produces neutral degradation products
  • Water soluble
  • Biodegradable and biocompatible

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Polyacetals: Water-Soluble, pH-Degradable Polymers with Extraordinary Temperature Response
Samanta S, et al.
Macromolecules, 49, 1858?1864-1858?1864 (2016)

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