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安全信息

938858

Sigma-Aldrich

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Polyvinyl alcohol

别名:

Poly(vinyl alcohol), Polyvinyl alcohol

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About This Item

线性分子式:
[-CH2CHOH-]n
CAS号:
MDL编号:
UNSPSC代码:
12352104
应用:
advanced drug delivery
filtration

描述

80% hydrolyzed

质量水平

表单

crystals

落球

2.5-3.5 cP, 4 % in water(20 °C)

应用

advanced drug delivery
filtration

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

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应用

NanoFabTx™ Polymers for Microneedles are carefully selected polymers that can be used to formulate microneedle patches. Microneedles are tiny projections of polymeric needles that can vary in length, pitch, and array for topical drug delivery applications. They are typically composed of biodegradable synthetic or natural polymers at a variety of suitable concentrations.
Polyvinyl alcohol (PVA) is a synthetic water-soluble polymer and it widely used in many drug delivery applications. It is a biocompatible polymer which is available in different molecular weights. The formation of the microneedles depends on the molecular weight and concentration of PVA.
The NanoFabTx™ Polymers for Microneedles can be used with the microneedle templates to formulate microneedles that can be used for several applications, such as delivering various therapeutic molecules and vaccine antigens via the skin.
The selected polymer will enable users to:
1) save time in polymer selection by providing a starting point to formulate microneedles and avoiding lengthy trial-and-error optimization.
2)formulate microneedles for various drug delivery applications.

法律信息

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

No data available

闪点(°C)

No data available

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development
Larra?eta E, et al.
Material Science and Engineering with Advanced Research, 104, 1-32 (2016)
Keegan Braz Gomes et al.
International journal of pharmaceutics, 613, 121393-121393 (2021-12-21)
Effective vaccines delivered via painless methods would revolutionize the way people approach vaccinations. This study focused on the development of fast-dissolving microneedles (MNs) to deliver antigen-loaded sustained release polymeric nanoparticles (NPs), achieving a dual-delivery platform for vaccination through the skin.

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