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Merck
CN

937606

Sigma-Aldrich

Dipyridyl dithiocarbonate

≥95%

别名:

DPDTC, Di-2-pyridyl dithiocarbonate

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About This Item

经验公式(希尔记法):
C11H8N2OS2
CAS号:
分子量:
248.32
MDL编号:
UNSPSC代码:
12352142
NACRES:
NA.21

质量水平

方案

≥95%

表单

powder or crystals

颜色

off-white to yellow, to Beige

官能团

thioether

储存温度

2-8°C

SMILES字符串

O=C(SC1=NC=CC=C1)SC2=NC=CC=C2

InChI

InChI=1S/C11H8N2OS2/c14-11(15-9-5-1-3-7-12-9)16-10-6-2-4-8-13-10/h1-8H

InChI key

BMMLAAKESBFUOH-UHFFFAOYSA-N

一般描述

Dipyridyl dithiocarbonate, or DPDTC, as reported by the Lipshutz lab, is an effective peptide coupling reagent that is active across a broad substrate scope under mild conditions. Additionally, as DPDTC is functionally similar to thioesters utilized in biological peptide formation, it can be utilized in aqueous media, and avoids many of the hazardous side products and safety concerns present in many other current peptide coupling strategies.

特点和优势

Functional in water
Broad substrate scope
Usable under mild conditions
Avoids hazardous coupling reagents

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Direct formation of amide/peptide bonds from carboxylic acids: no traditional coupling reagents, 1-pot, and green
Freiberg M K, et al.
Chemical Science, 14(13), 3462-3469 (2023)

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