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质量水平
方案
≥95%
表单
solid
颜色
white to off-white
储存温度
2-8°C
SMILES字符串
OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O)=O
InChI
InChI= 1S/C33H39N5O6/c1-20(2)29(38-33(43)44-19-27-25-10-5-3-8-23(25)24-9-4-6-11-26(24)27)31(41)37-28(12-7-17-35-32(34)42)30(40)36-22-15-13-21(18-39)14-16-22/h3-6,8-11,13-16,20,27-29,39H,7,12,17-19H2,1-2H3,(H,36,40)(H,37,41)(H,38,43)(H3,34,35,42)/t28-,29-/m0/s1
应用
This is a cathepsin cleavable linker used in the construction of antibody drug conjugates (ADC & Bioconjugation).
其他说明
Bifunctional Cathepsin cleaveable linkers
ADC & Bioconjugation
Chemical Biology Tools
Impact of linker length on the activity of PROTACs
ADC & Bioconjugation
Chemical Biology Tools
Impact of linker length on the activity of PROTACs
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
从最新的版本中选择一种:
Cryptophycin-55/52 based antibody-drug conjugates: Synthesis, efficacy, and mode of action studies
European Journal of Medicinal Chemistry, 199, 112364-112364 (2020)
EGFR Targeted Cetuximab-Valine-Citrulline (vc)-Doxorubicin Immunoconjugates- Loaded Bovine Serum Albumin (BSA) Nanoparticles for Colorectal Tumor Therapy
International journal of nanomedicine, 26, 2443-2459 (2021)
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