质量水平
检测方案
≥95%
形式
powder or crystals
颜色
white to off-white
mp
163-164 °C
储存温度
−20°C
SMILES字符串
OC(CCC(N1CC2=CC=CC=C2C#CC3=CC=CC=C13)=O)=O
InChI
InChI=1S/C19H15NO3/c21-18(11-12-19(22)23)20-13-16-7-2-1-5-14(16)9-10-15-6-3-4-8-17(15)20/h1-8H,11-13H2,(H,22,23)
应用
DBCO Acid is a bifunctional building block comprising of an acid terminus useful for reaction with amine containing linkers in presence of activators such as EDC or HATU and a dibenzocyclooctyne (DBCO) terminus useful for copper-free click chemistry.
特点和优势
DBCO compounds react with azides without need of Cu(I) catalyst due to the strained nature of alkyne resulting in formation of fast and stable triazole linkage.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes
Rostovtsev V V, et al.
Angewandte Chemie (International ed. in English), 41, 2596-2599 (2002)
Copper-free click chemistry in living animals
Chang P V, et al.
Proceedings of the National Academy of Sciences of the USA, 107, 1821-1826 (2010)
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