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一般描述
Poly(glycerol sebacate) (PGS) is a biodegradable polymer with tunable mechanical properties that can be used in soft tissue engineering and regenerative medicine applications. It is non-immunogenic, non-cytotoxic and has minimal inflammatory response. The polymer backbone and crosslinks can undergo hydrolytic degradation due to the presence of ester linkages. The ester bonds in the polymer backbone covalently crosslink at high temperature (>130 °C) under vacuum without using any toxic crosslinkers to form a three-dimensional (3D) network of random coils.
应用
- Scaffold material synthesis like blood vessels, cornea and nerve tissue
- In orthopedic implants
- In the drug delivery system and bioelectronic applications
特点和优势
- Flexible elastomer with tunable mechanical properties
- Higher reversible deformation properties
- Shape memory
- Bioresorbable polymer
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Poly(Glycerol Sebacate) in Biomedical Applications-A Review of the Recent Literature
Vogt L, et al.
Advanced Healthcare Materials, 10, e2002026-e2002026 (2021)
Synthesis, Characterization and 3D Micro-Structuring via 2-Photon Polymerization of Poly(glycerol sebacate)-Methacrylate?An Elastomeric Degradable Polymer
Tala, et al.
Frontiers in physics, 6, 41-41 (2018)
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