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Merck
CN

93550

托品碱

≥97.0% (NT)

别名:

品托碱

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关于此项目

经验公式(希尔记法):
C8H15NO
化学文摘社编号:
分子量:
141.21
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
204-384-2
Beilstein/REAXYS Number:
80188
MDL number:
Assay:
≥97.0% (NT)
Form:
powder
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InChI

1S/C8H15NO/c1-9-6-2-3-7(9)5-8(10)4-6/h6-8,10H,2-5H2,1H3/t6-,7+,8+

InChI key

CYHOMWAPJJPNMW-JIGDXULJSA-N

SMILES string

CN1[C@H]2CC[C@@H]1C[C@H](O)C2

assay

≥97.0% (NT)

form

powder

impurities

0-3% water

solubility

H2O: 0.1 g/mL, clear

functional group

hydroxyl

storage temp.

2-8°C

Quality Level

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Gábor Maksay et al.
Bioorganic & medicinal chemistry, 17(19), 6872-6878 (2009-09-04)
Heteroaromatic carboxylic esters of (nor)tropine were synthesized. Tropine esters displaced [(3)H]strychnine binding to glycine receptors of rat spinal cord with low Hill slopes. Two-site displacement resulted in nanomolar IC(50,1) and micromolar IC(50,2) values, and IC(50,2)/IC(50,1) ratios up to 615 depending
Heike Kaiser et al.
Planta, 225(1), 127-137 (2006-07-18)
Tropinone reductases (TRs) are essential enzymes in the tropane alkaloid biosynthesis, providing either tropine for hyoscyamine and scopolamine formation or providing pseudotropine for calystegines. Two cDNAs coding for TRs were isolated from potato (Solanum tuberosum L.) tuber sprouts and expressed
A Yamashita et al.
Biochemistry, 38(24), 7630-7637 (1999-07-01)
Tropinone reductase-II (TR-II) catalyzes the NADPH-dependent reduction of the carbonyl group of tropinone to a beta-hydroxyl group. The crystal structure of TR-II complexed with NADP+ and pseudotropine (psi-tropine) has been determined at 1.9 A resolution. A seven-residue peptide near the
Birgit Dräger
Phytochemistry, 67(4), 327-337 (2006-01-24)
Two stereospecific oxidoreductases constitute a branch point in tropane alkaloid metabolism. Products of tropane metabolism are the alkaloids hyoscyamine, scopolamine, cocaine, and polyhydroxylated nortropane alkaloids, the calystegines. Both tropinone reductases reduce the precursor tropinone to yield either tropine or pseudotropine.
Rawia Zayed et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 59(11-12), 863-867 (2005-01-26)
Hairy root cultures of Brugmansia suaveolens were set up by infection of root tips with Agrobacterium rhizogenes. The successful transformation was confirmed by analysing rolC and virC genes using polymerase chain reaction (PCR). Hairy root cultures were employed to study

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