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表单
powder or crystals
质量水平
反应适用性
reagent type: linker
官能团
Boc
carboxylic acid
储存温度
2-8°C
SMILES字符串
O=C(O)C(CC1)CCN1CC(CC2)OC32CN(C(OC(C)(C)C)=O)C3
InChI key
CVHPZSHLWZEYQS-UHFFFAOYSA-N
应用
1-((2-(tert-Butoxycarbonyl)-5-oxa-2-azaspiro[3.4]octan-6-yl)methyl)piperidine-4-carboxylic acid is useful as a rigid linker in PROTAC development for targeted protein degradation as well as chemical conjugates. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties. Developed in partnership with ComInnex.
其他说明
法律信息
Practum is a registered trademark of Sartorius Lab Instruments GmbH & Co. KG
相关产品
产品编号
说明
价格
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
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