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质量水平
方案
≥95%
表单
liquid
折射率
n/D 1.454
密度
1.062 g/mL
储存温度
−20°C
SMILES字符串
[S](=NOC(C)(C)C)=O
InChI
1S/C4H9NO2S/c1-4(2,3)7-5-8-6/h1-3H3
InChI key
QNDHWAYLAJVRCB-UHFFFAOYSA-N
应用
t-BuONSO is a stable reagent active for the synthesis of primary sulfonamides when used in conjunction with organolithium or Grignard reagents. t-BuONSO is tolerant of a variety of alkyl and aryl substrates and can be used in the synthesis of many medicinally relevant compounds.
警示用语：
Danger
危险声明
危险分类
Resp. Sens. 1 - Self-react. C - Skin Sens. 1
储存分类代码
5.2 - Organic peroxides and self-reacting hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Ze-Xin Zhang et al.
Journal of the American Chemical Society, 141(33), 13022-13027 (2019-08-10)
Sulfondiimines-the double aza-analogues of sulfones-hold significant potential as leads in discovery chemistry, yet their application in this arena has been held back by the scarcity of appropriate synthetic routes. Existing methods employ sulfides as substrates, and rely on consecutive imination
Thomas Q Davies et al.
Organic letters, 22(24), 9495-9499 (2020-11-26)
Sulfonamides have played a defining role in the history of drug development and continue to be prevalent today. In particular, primary sulfonamides are common in marketed drugs. Here we describe the direct synthesis of these valuable compounds from organometallic reagents
Thomas Q Davies et al.
Journal of the American Chemical Society, 142(36), 15445-15453 (2020-08-26)
Sulfoximines and sulfonimidamides are promising compounds for medicinal and agrochemistry. As monoaza analogues of sulfones and sulfonamides, respectively, they combine good physicochemical properties, high stability, and the ability to build complexity from a three-dimensional core. However, a lack of quick
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