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应用
PEI Prime ™是一种阳离子聚合物，设计用于高产、可重复和可放大的药物和基因递送。作为基因载体，PEI通过带负电的核酸磷酸基团和带正电的PEI胺基之间的静电自组装与核酸形成复合物。由于这种相互作用，PEI 作为基因载体被研究人员广泛研究，并且是通过内吞作用将核酸递送到细胞中的最有效的合成聚合物之一。
PEI Prime ™采用优化的 PEI 形式来减少性能差异并加快工艺开发时间。每批 PEI Prime ™都用 SEAP 报告基因进行三次重复的定量性能测试。PEI Prime ™是经济有效地生产任何生物制品（包括重组蛋白、抗体和病毒）的绝佳选择。
PEI Prime ™采用优化的 PEI 形式来减少性能差异并加快工艺开发时间。每批 PEI Prime ™都用 SEAP 报告基因进行三次重复的定量性能测试。PEI Prime ™是经济有效地生产任何生物制品（包括重组蛋白、抗体和病毒）的绝佳选择。
法律信息
PEI Prime is a trademark of Serochem LLC
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
S M Zou et al.
The journal of gene medicine, 2(2), 128-134 (2000-05-16)
Several nonviral vectors including linear polyethylenimine (L-PEI) confer a pronounced lung tropism to plasmid DNA when injected into the mouse tail vein in a nonionic solution. and results We have optimized this route by injecting 50 microg DNA with excess
W T Godbey et al.
Biomaterials, 22(5), 471-480 (2001-02-24)
Poly(ethylenimine) (PEI) was used to transfect the endothelial cell line EA.hy 926, and the secreted levels of three gene products, tissue-type plasminogen activator (tPA), plasminogen activator inhibitor type 1 (PAI-1), and von Willebrand Factor (vWF), were assessed via ELISA. We
L Wightman et al.
The journal of gene medicine, 3(4), 362-372 (2001-09-01)
Efficient gene transfer is a major challenge for non-viral gene therapy. Understanding how non-viral vectors initiate gene expression could lead to the development of new future vectors with enhanced efficacy. Linear or branched polyethylenimine (PEI)/DNA complexes were generated in varying
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