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Merck
CN

918636

Sigma-Aldrich

低内毒素 GelMA 溶液

gel strength 300 (bloom), degree of substitution 80%, 0.2 μm, sterile-filtered, GelMA Type B

别名:

GelMA, 明胶甲基丙烯酰基, 明胶甲基丙烯酰胺, 明胶甲基丙烯酸酯

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About This Item

UNSPSC代码:
12352202
NACRES:
NA.23

质量水平

无菌性

sterile-filtered

形式

viscous liquid

浓度

20 wt. % in DPBS (buffer)

杂质

≤5 CFU/g Bioburden (Fungal)
≤5 CFU/g Bioburden(Aerobic)
<25 EU/mL Endotoxin

颜色

colorless to pale yellow

粒径

0.2 μm

pH值(酸碱度)

6.5-7.5

储存温度

−20°C

应用

低内毒素 GelMA 溶液是溶于 DPBS 缓冲液中的 20% 低内毒素甲基丙烯酸酯化明胶(GelMA) 溶液。它通过 0.2μ m 无菌过滤器进行无菌过滤,可直接用于生物医学应用。
GelMA 可用于形成用于组织工程和 3D 生物打印的水凝胶。明胶甲基丙烯酰基(GelMA)是一种可聚合的水凝胶材料,衍生自天然细胞外基质(ECM)成分。由于其低成本,丰富性和天然细胞结合基序的保留,明胶已成为组织工程应用中高度寻求的材料。在GelMA中添加可光交联的甲基丙烯酰胺官能团可合成在生物学相关条件下稳定并促进细胞粘连,扩散和增殖的生物相容性,可生物降解和非免疫原性水凝胶。

包装

10 mL 玻璃瓶包装

WGK

WGK 3

法规信息

含少量动物源组分生物产品

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Preparation and characterization of gelatin-poly(methacrylic acid) interpenetrating polymeric network hydrogels as a pH-sensitive delivery system for glipizide.
Gupta V N, et al.
Indian Journal of Pharmaceutical Sciences, 69(1), 64-68 (2007)
Xin Zhao et al.
Advanced healthcare materials, 5(1), 108-118 (2015-04-17)
Natural hydrogels are promising scaffolds to engineer epidermis. Currently, natural hydrogels used to support epidermal regeneration are mainly collagen- or gelatin-based, which mimic the natural dermal extracellular matrix but often suffer from insufficient and uncontrollable mechanical and degradation properties. In
Kelly M C Tsang et al.
Advanced functional materials, 25(6), 977-986 (2015-09-04)
Hydrogels are often employed as temporary platforms for cell proliferation and tissue organization in vitro. Researchers have incorporated photodegradable moieties into synthetic polymeric hydrogels as a means of achieving spatiotemporal control over material properties. In this study protein-based photodegradable hydrogels
Anh H Nguyen et al.
Acta biomaterialia, 13, 101-110 (2014-12-03)
Gelatin has been commonly used as a delivery vehicle for various biomolecules for tissue engineering and regenerative medicine applications due to its simple fabrication methods, inherent electrostatic binding properties, and proteolytic degradability. Compared to traditional chemical cross-linking methods, such as
Jason W Nichol et al.
Biomaterials, 31(21), 5536-5544 (2010-04-27)
The cellular microenvironment plays an integral role in improving the function of microengineered tissues. Control of the microarchitecture in engineered tissues can be achieved through photopatterning of cell-laden hydrogels. However, despite high pattern fidelity of photopolymerizable hydrogels, many such materials

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