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Merck
CN

916145

Sigma-Aldrich

Poly((R)-3-hydroxybutyrate-co-(R)-3-hydroxyvalerate-co-(R)-3-hydroxyhexanoate)

natural origin, PHH content 4.1 %, PHV content 2.3 %

别名:

PHB, PHBH, PHBV, Polyhydroxybutyrate

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About This Item

线性分子式:
[C4H6O2]x[C5H8O2]y[C6H10O2]z
UNSPSC代码:
12162002
NACRES:
NA.23

质量水平

表单

powder

分子量

average Mn 1,000,000

组成

3-Hydroxyhexanoic acid content, 4.1%
3-Hydroxyvaleric acid content, 2.3%
PHH content, 4.1%
PHV content, 2.3%

颜色

white to off-white

应用

Poly((R)-3-hydroxybutyrate-co-(R)-3-hydroxyvalerate-co-(R)-3-hydroxyhexanoate) is a biocompatible and biodegradable polymer produced by fermentation of genetically modified microorganisms. Poly(3-hydroxybutyric acid) (PHB) is a common polyhydroxyalkanoate (PHA), it has been widely used for food packaging, medical implants, biodegradable sutures and drug delivery systems due to its biocompatible and biodegradable properties. PHB has been investigated as drug delivery micro- and nano-carriers.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Anupama Shrivastav et al.
BioMed research international, 2013, 581684-581684 (2013-08-29)
Drug delivery technology is emerging as an interdisciplinary science aimed at improving human health. The controlled delivery of pharmacologically active agents to the specific site of action at the therapeutically optimal rate and dose regimen has been a major goal
Sumeet Kapoor et al.
International journal of pharmaceutics, 511(2), 876-889 (2016-08-06)
Faster biodegradation, immunogenicity and lack of cell penetrative capabilities are hurdles in development of peptidyl drugs for cancer therapy. Polymeric carriers can be used to overcome these problems. The present study is focused on the use of polyhydroxybutyrate as a
K Juni et al.
Critical reviews in therapeutic drug carrier systems, 3(3), 209-232 (1987-01-01)
Poly(hydroxy acids) so far have been examined for use in drug delivery in limited number, while the advantageous use of the polymers has been recognized due to their biodegradability and biocompatibility. Homo- and copolymers of lactic acid and glycolic acid

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