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Merck
CN

914010

Sigma-Aldrich

4-Nitrophenyl (2-(vinyloxy)ethyl) carbonate

≥95%

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别名:
Light-initiated bioorthogonal photoclick cycloaddition reagent, VE, Vinyl ether photoclick reagent
经验公式(希尔记法):
C11H11NO6
分子量:
253.21
UNSPSC代码:
12352200

检测方案

≥95%

形式

liquid

储存温度

−20°C

应用

4-Nitrophenyl (2-(vinyloxy)ethyl) carbonate is a vinyl ether photoclick reagent (VE) mediated by visible light for bioorthogonal reaction with a 9,10-phenanthrenequinone (PQ) photoclick reagent (see cat# 913766) for increased spatiotemporal control within biological applications. Signficantly, analysis of reactivity suggests this photoclick reaction is orthogonal to azide-alkyne and UV-mediated tetrazole-ene photoclick reactions, allowing for various means of simulteneous labeling of biomolecules in a given sample. This method requires no catalyst and is reported to be compatible with cells.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

相关产品

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Jinbo Li et al.
Journal of the American Chemical Society, 140(44), 14542-14546 (2018-10-24)
Here we report a visible light-triggered, catalyst free bioorthogonal reaction that proceeds via a distinct pathway from reported bioorthogonal reactions. The prototype of this bioorthogonal reaction was the photocycloaddition of 9,10-phenanthrenequinone with electron-rich alkenes to form fluorogenic [4+2] cycloadducts. The

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